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Research Topics

​The Medical Data Scien​​​ce research department develops data-driven methods and digital infrastructures to improve medical care and research in the long term. We combine expertise from medical informatics, statistics, artificial intelligence, software engineering, and clinical research to make complex health data secure, interoperable, and evidence-based.

Our goal is to bridge the gap between patient​​ data, clinical practice, and medical research through interdisciplinary research and technological innovation—for more precise, personalized, and secure healthcare in the future. 

The work of the Medical Data Science department currently focuses on f​​our key research areas:

Digital infrastructures for patient care and medical research

​​We develop and evaluate digital infrastructures that support efficient patient care processes and enab​​le high-quality medical research. Our work focuses on the integration of clinical workflows, data interoperability, and secure information management to foster innovation and improve healthcare delivery.

Key research di​​​rections​​​ include:

  • Federated analysis infrastructures, such as Personal Health Train, FLAME and others
  • Privacy preserving record linkage methods and tool chains

Projects: PrivateAIM, SafeLink (PPRL), PATH, AMPEL

Analysis of patient care data

Our research focuse​s on the systematic analysis of patient care data to uncover patterns, enhance clinical decision-making, and improve healthcare quality. By integrating advanced data analytics with evidence-based approaches, we aim to translate complex medical information into actionable insights for better patient outcomes and healthcare delivery.

Key research directions inclu​d​​e:

  • Developing predictive analytics for early detection and outcome forecasting
  • Mining electronic health records to identify trends and inefficiencies in care
  • Evaluating the impact of clinical interventions on patient safety and recovery
  • Designing data-driven tools to support personalized and efficient healthcare
​Projects: DiaClusT, NutriScoPe, LinCare​​

AI methods for (clinical) decision support

Our research group develops advanced artificial intelligence methods to enhance clinical decision support through the analysis of electronic health records (EHRs) and multimodal data integration. By combining structured clinical data, medical imaging, laboratory results, and patient narratives, we design machine learning and deep learning models that generate comprehensive, data-driven insights to assist clinicians in diagnosis, prognosis, and tr​eatment planning. Our work also emphasizes explainable and trustworthy AI, ensuring that the developed systems are transparent, ethically grounded, and reliable for real-world healthcare applications.

Projects: LeukoExpert, Tag-White, AMPEL​, Made In Saxony​

Synthetic medical data generation

Advanced generative modeling techniques, such as Generative Adversarial Networks (GANs) and Variational Autoen​coders (VAEs), are employed to generate realistic, privacy-preserving medical data that address key challenges in clinical research, including limited data availability and strict privacy constraints. By generating synthetic datasets that accurately capture the statistical properties of real medical data without exposing sensitive information, this work enhances data accessibility and supports robust machine learning development and implementation. The research focuses on evaluating the fidelity and downstream utility of synthetic data across structured and unstructured modalities, with the goal of improving model generalizability, reproducibility, and performance in medical diagnosis, prognosis, and clinical decision support.

Projects: SynDat​​​
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