Projects

The main research activities of the Medical Department III focus on

  • Obesity
  • Diabetes mellitus / insulin resistance and
  • Adipose tissue dysfunction.

Our research projects are supported by a number of different sources including the Federal Ministry of Education and Research (BMBF), the German Research Foundation (DFG), and several other granting agencies.

Collaborative Research Center "Mechanisms of Obesity"

​This collaborative research center (Sonderforschungsbereich SFB 1052) is sponsored by the German Research Foundation "Deutsche Forschungsgemeinschaft" (DFG) and has started at the beginning of the year 2013 at the Faculty of Medicine at the University Leipzig. The CRCs speaker is Prof. Dr. Matthias Blüher and the vice speaker is Prof. Dr. Michael Stumvoll. Further information on the basic research projects of this CRC can be found on the website of the SFB 1052.

​Integrated Research and Treatment Center (IFB) AdiposityDiseases

​The IFB AdiposityDiseases is a joint center of the Medical Faculty of the University Leipzig and the University Hospital IFB Plus Symbol  Leipzig. It is sponsored by the Federal Ministry of Education and Research. The IFB cooperates with many hospitals and institutes of the University Hospital and the University. Scientific Director of the IFB AdiposityDiseases is Prof. Dr. Michael Stumvoll.

Further information

​Helmholtz-Institute of Metabolism, Adiposity, and Vascular function (HI-MAG)

​The HI-MAG was founded by the Helmholtz Zentrum München - German Research Center for Environmental Health and the University of Leipzig. Its main research focus is the biology of adipose tissue, energy metabolis, and the effects of vascular function.

Detailed information will follow soon.

​Imaging and Curing Environmental Metabolic Diseases (ICEMED)

​The Helmholtz Alliance ICEMED – Imaging and Curing Environmental Metabolic Diseases – is a network of synergistic excellence representing a worldwide unique research consortium of biomedical research scientists, clinicians and cutting edge metabolic imaging experts in Germany with the goal to improve our understanding of the brain in metabolic diseases. Prof. Dr. Michael Stumvoll and Prof. Dr. Matthias Blüher from our Department participate on the ICEMED's projects.

Further information

​International Research Project MetaCardis

​In this project, a consortium of 14 research institutions and companies in France, Germany, England, Denmark, Sweden and Belgium investigate how the human intestinal microbiome relates to the development of cardiovascular and metabolic diseases. 

Further information

​Diabetes Studies of the German Center for Diabetes Research (DZD)

​The Diabetes Studies of the German Center for Diabetes Research (DZD) combine basic science, translational research projects, and clinical trials focussing on diabetes mellitus. We are a study-center of three DZD studies: the German Prediabetes Intervention-Study (PLIS), the German Study Gestational Diabetes (PREG) and the German Diabetes Study (DDS).

Further information

​Leipzig Research Center for Civilization Diseases (LIFE)

​The Leipzig Research Center for Civilization Diseases (LIFE) investigates several civilization diseases including diabetes mellitus, cardiovascular diseases, depression, and allergies in a longitudinal cohort comprising of a representative sample of the Leipzig population. Furthermore, the LIFE Research Center is one of 18 study-centers of the German National Cohort (NAKO).

Further information

​Leptin Treatment Center Leipzig

​The Leptin Treatment Center Leipzig provides leptin treatment for patients with lipodystrophy as one of only 6 centers in Europe. Heads of the Leptin Treatment Center Leipzig are Prof. Dr. Michael Stumvoll and Prof. Dr. Mathias Faßhauer.

Contact details can be found here.

​easyLINKAGE - A graphical user interface for
automated linkage analyses

​easyLINKAGE is a joint project of the Institute of Human Genetics, Charité Virchow Campus Berlin and the Division of Nephrology, Department of Medicine, Neurology, and Dermatology, University Clinic Medical Leipzig. We extended the original easyLINKAGE program by enabling linkage analyses for large-scale SNP data in addition to those of microsatellites. We implemented new modules for Allegro, Merlin, SimWalk, GeneHunter Imprinting, GeneHunter TwoLocus, SuperLink and extended FastSLink by automatic loop breaking and new outputs. We added conditional linkage analyses as well as multipoint simulation studies, and extended error test routines by checking for Mendelian/non-Mendelian genotyping errors and for deviations from Hardy–Weinberg equilibrium. Data can be analyzed in sets of markers, in defined centimorgan intervals and by using different allele frequency algorithms. The outputs consist of genome-wide as well as chromosomal postscript plots of LOD scores, NPL scores, P-values and other parameters.

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