Serotonin-Ttransporter-availability in patients with depressive disorders and obsessive-compulsive disorders

​Research staff

PD. Dr. Katarina Stengler, PD Dr. P. Schönknecht, K. Nägler, Dr. E. Hammerstein, Prof. U. Hegerl

Cooperation partner

• Prof. Dr. med. Osama Sabri (Department of Nuclear Medicine, University Medical Centre Leipzig)
• Dr. med. Swen Hesse (Department of Nuclear Medicine, University Medical Centre Leipzig)

Finance

Medical Faculty

Aim

Primary objectives:

In vivo quantification of the central SERT-availability in neuropsychiatric diseases: SERT-Distributions-Volume and bonding potential

Secondary objectives:

• Correlation between the occurence of the according clinical syndrom and the activity of the serotonerg system
• Description of differences in consideration to the serotonerg system between patients and healthy people and patients with different disorders (specification and subtyping) among each other

Study design

open, monocentric diagnostic study, in cross-section with untreated patients compared to healthy control persons and patients with related mental disorders