Research Projects

The Faculty of Medicine provides excellent conditions for diverse areas of research – basic research as well as clinical research – applying advanced methods and technologies.

Promoting an environment of constructive and creative exchange the Faculty of Medicine is an outstanding research facility – especially for Junior Scientists.

​This page provides an overview of selected research projects with funding of over 500.000 EUR for the Faculty of Medicine.​

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German Research Foundation (DFG)

The Faculty of Medicine is currently coordinating its own DFG/collaborative research centre (CRC 1052) and is considerably involved in CRC 1423. In addition to two graduate schools and a Junior Research Group in the Emmy Noether Programme, a Heisenberg professor also conducts research at the Leipzig site.​​


Clinical Studies ​

EFFECT of daily antiseptic body wash with octenidine on nosocomial primary bacteraemia and nosocomial multidrugresistant organisms in intensive care units
Project Manager: Prof. Dr. Iris F. Chaberny
Project Duration: 2015 – 2022

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MUC-FIRE – A randomized multicenter open-label controlled trial to show that mucous fistula refeeding reduces the time from enterostomy closure to full enteral feeds (MUCous FIstula REfeeding ("MUC-FIRE") trial)​
Project Manager: Prof. Dr. Martin Lacher 
Project Duration: 2017 – 2022

Find-AF2 – Intensive heart rhythm monitoring to decrease ischemic stroke and systemic embolism
Project Manager: Prof. Dr. Rolf Wachter 
Project Duration: 2019 – 2023​

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STIM-ADHD – A parallel randomized double-blind sham-controlled multicenter trial of transcranial direct current stimulation (tDCS) in adult attention deficit hyperactivity disorder​
Project Manager: PD Dr. Maria Strauß
Project Duration: 2021 – 2024


European Union

Coordinated collaborative p​​​rojects


PAPA-ARTIS – Paraplegia Prevention in Aortic Aneurysm Repair by Thoracoabdominal Staging with ‘Minimally-Invasive Segmental Artery Coil-Embolization’: A Randomized Controlled Multicentre Trial­
Project Manager: Prof. Dr. Christian Etz
Project Duration: 2017 – 2022


Joint Projects with EU-funding over 500.000 Euro​​


BETA3_LVH – A multi-center randomized, placebo-controlled trial of mirabegron, a new beta3-adrenergic receptor agonist on left ventricular mass and diastolic function in patients with structural heart disease​­
Project Manager: Dr. Oana Brosteanu​
Project Duration: 2015 – 2022

 

imSAVAR – Immune Safety Avatar: nonclinical mimicking of the immune system effects of immunomodulatory therapies 
Project Manager: Prof. Dr. Markus Löffler
Project Duration: 2019 – 2025

A-TANGO –​ Novel combinatorial treatment of acute-on-chronic liver failure
Project Manager: Prof. Dr. Thomas Berg
Project Duration: 2021 – 2026


European Research Council (ERC)

The following researchers of our faculty are funded with ERC Grants:

Prof. Dr. Stefan Hallermann
ERC Consolidator Grant – PreSynPlast - Molecular mechanisms of presynaptic plasticity
Laufzeit: 2020 – 2025


Prof. Dr. Ruth Stassart
ERC Starting Grant – AxoMyoGlia – Spatio-functional cellular interplay in peripheral nerve diseases
Project Duration: 2021 – 2025 

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Federal Ministry of Education and Research

Project funding from the Federal Ministry of Education and Research makes a significant contribution to the research performance of our university. Our currently funded and recently completed projects with a funding amount of over 500,000 EUR are listed below:

​​​NAKO – The Health Study: Causes of common diseases in the interplay of genetic predisposition, lifestyle habits and environmental factors
Project Manager: Prof. Dr. Markus Löffler 
Project Duration: 2014 – 2023

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AgE-health.de: Improving care of late-life depression: Acceptability, effectiveness and cost-effectiveness of a web-based self-management program for prolonged grief (Junior Research Group Health Care Research)​
Project Manager: Dr. Janine Stein 
Project Duration: 2016 – 2022


SMITH: Smart Medical Information Technology for Healthcare
Head of the Consortium​:  Prof. Dr. Markus Löffler 
Project Duration: 2016 – 2023

SMITH –​ Junior Research Group Development of a Terminology and Ontology-based Phenotyping Framework
Project Manager: Dr. Alexander Uciteli
Project Duration: 2021-2024


AgeWell.de – A multi-centric cluster-randomized controlled prevention trial in primary care​
Project Manager: Prof. Dr. Steffi G. Riedel-Heller 
Project Duration: 2017 – 2022


COMPASS – Comprehensive Surgical Landscape Guidance System for Immersive Assistance in Minimally-invasive and Microscopic Interventions 
Project Manager: Prof. Dr. Thomas Neumuth 
Project Duration: 2018 – 2022


ToSEE – Treatment of Established Status Epilepticus in the Elderly
Project Manager: Prof. Dr. Joseph Claßen 
Project Duration: 2018 – 2023


AMIS II – Analyzing pathways from childhood maltreatment to internalizing symptoms and disorders in children and adolescents​​ 
Project Manager: Prof. Dr. Kai von Klitzing 
Project Duration: 2019 – 2023


MR-Thrombosis-Theranostic – MR-guided minimally-invasive Diagnosis and Therapy of Thrombosis
Project Manager: Prof. Dr. Andreas Melzer
Project Duration: 2019 – 2022


MR-Stent – MR-guided Stent-Implantation
Project Manager: Prof. Dr. Andreas Melzer
Project Duration: 2019 – 2022


MPM – Models for Personalized Medicine​
Project Manager: Prof. Dr. Thomas Neumuth
Project Duration: 2019 – 2022


MOMENTUM –​ Mobile medical technology for the integrated emergency care and trauma medicine​
Project Manager: Prof. Dr. Thomas Neumuth 
Project Duration: 2019 – 2022


AECOPD – Nasal high-flow compared to non-invasive ventilation in treatment of acute acidotic hypercapnic exacerbation of chronic obstructive pulmonary disease 
Project Manager: Prof. Dr. med. Hubert Wirtz
Project Duration: 2020 – 2022



CoRaLa II – Long-term need of ranibizumab injections with or without early targeted peripheral laser photocoagulation for treatment of macular edema due to central retinal vein occlusion
Project Manager: Prof. Dr. med. Matus Rehak 
Project Duration: 2020 – 2023


SUCCEED-F –​ Studie häufiger Umweltexpositionen und Krankheiten im Kindes- und Jugendalter: Machbarkeit
Project Manager: Prof. Dr. med. Antje Körner 
Project Duration: 2020 – 2023


SYMPATH – Systems Medicine of Pneumonia Aggravated Atherosclerosis​
Project Manager: Prof. Dr. Markus Scholz 
Project Duration: 2020 – 2023


POLAR_MI – POLypharmacy – Drug interActions – Risks
Project Manager: Prof. Dr. Markus Löffler 
Project Duration: 2020 – 2022​



NAMIBIO App – Food Allergy Biomarker Application Consortium​
Project Manager: Prof. Jon Genuneit

Project Duration: 2021 – 2024

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@ktivPLUS – Adipositas und Depression – Entwicklung, Akzeptanz, Wirksamkeit und Kosteneffektivität eines selbsthilfestärkenden Online-Coaches
Project Manager: Dr. rer. med. Margrit Löbner
Project Duration: 2022 –​ 2027

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3MP-FUS – Neuromodulation in rare neuropsychiatric disorders with focused ultrasound
Project Manager: Prof. Dr. Andreas Melzer​
Project Duration: 2022 – 2025

COMPLETE NSTEMI – Complete revascularization versus culprit lesion only PCI in NSTEMI​
Project Manager: Univ.-Prof. Dr. med. Holger Thiele
Project Duration: 2022 – 2026​

6G-Health – ​High-performance 6G networking for distributed medical technology
Project Manager: Prof. Dr. Thomas Neumuth 
Project Duration: 2022 – 2025

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​​​FOMO – Nanoporous, form-fitting glass monoliths as drug depot systems for targeted drug delivery in dentistry 
Project Manager: PD Dr. rer. nat. Andreas König​ 
Project Duration: 2022 – 2025

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Federal Ministry for Economic Affairs and Climate Action

​KliNet5G – KliNet5G - Clinical Networks via 5G
Project Manager: Prof. Dr. Thomas Neumuth
Project Duration: 2022 – 2025

MediNet – MediNet - Intelligent digital platform for the location- and time-independent medicine of the future
Project Manager: Prof. Dr. Thomas Neumuth​
Project Duration: 2022 – 2026​​


Federal Ministry of Labour and Social Affairs

LIPSY – Leipziger Individual Placement and Support for people with mental illnesses​
Project Manager: Prof. Dr. Steffi G. Riedel-Heller
Project Duration: 2020 – 2025

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Federal Joint Committee

@aktiv_rollout – How can translation be successful? Implementation of self-help strengthening online coaches in various treatment settings​
Project Manager: Dr. Margrit Löbner
Project Duration: 2020 – 2023​​

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Saxon State Ministry for Social Affairs and Social Cohesion

PostStroke Manager: mobile, digital system to strengthen relapse prevention, health competence and self-reliance
Project Manager: Prof. Dr. Dominik Michalski 
Project Duration: 2019 – 2023



AMPEL – Analysis and Reporting System for the Improvement of Patient Safety through Real-Time Integration of Laboratory Findings​
Project Manager: Dr. Thorsten Kaiser 
Project Duration: 2019 – 2022​


State Ministry of Economic Affairs, Labour and Transport

GMP-Knorpel – Erlangung einer Herstellungserlaubnis für die patientenindividuelle Herstellung eines neuartigen stammzellbasierten Zelltherapeutikums für fokale Knorpelschäden
Project Manager: Prof. Dr. Pierre Hepp 
Project Duration: 2019 – 2022


CC TOP – Development and validation of a novel cell isolation technology for therapeutic use in immuno-oncology​
Project Manager: Dr. Anja Grahnert
Project Duration: 2019 – 2022


Foundations

Foundations such as Deutsche Krebshilfe (German Cancer Aid), Else-Kröner-Fresenius-Foundation or the Volkswagen Foundation make a significant contribution to the promotion of our programs and projects. Our currently funded and recently completed projects with a funding amount of over 200,000 EUR are listed below:

Deutsche Krebshilfe


LUPE – Longitudinal analysis of mental disorders, psychosocial distress and psycho-oncological care needs of patients and their relatives stratified by biopsychosocial factors
Project Manager: Prof. Anja Mehnert-Theuerkauf
Project Duration: 2019 – 2022

OptiScreen – Optimized psycho-oncological care algorithm – from screening to intervention
Project Manager: P​rof. Anja Mehnert-Theuerkauf
Project Duration: 2019 – 2022

Volkswagen Stiftung

Innovative Approaches to Antiviral Drug Development​ –​ Peptide-based crystallographic fragment screening for fast and efficient discovery of lead structures against zoonotic viral diseases
Project Participants: Prof. Jens Meiler, Prof. Norbert Sträter, Prof. Ralf Hoffmann
Project Duration: 2021 – 2024

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Else-Kröner-Fresenius-Stiftung  

cAMP nanodomains and hypertension
Project Manager​: Prof. Dr. Andreas Bock
Project Duration: 2022 –​ 2024

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