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Research Projects

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The Faculty of Medicine provides excellent conditions for diverse areas of research – basic research as well as clinical research – applying advanced methods and technologies.

Promoting an environment of constructive and creative exchange the Faculty of Medicine is an outstanding research facility – especially for Junior Scientists.

​This page provides an overview of selected research projects with funding of over 500.000 EUR for the Faculty of Medicine.​

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Scientists doing research at the Medical Faculty of the University of Leipzig
Research Portal

German Research Foundation (DFG)

The Faculty of Medicine is currently coordinating its own DFG/collaborative research centre (CRC 1052) and is considerably involved in CRC 1423. In addition to two graduate schools and a Junior Research Group in the Emmy Noether Programme, a Heisenberg professor also conducts research at the Leipzig site.​​


Clinical Studies ​

​STIM-ADHD – A parallel randomized double-blind sham-controlled multicenter trial of transcranial direct current stimulation (tDCS) in adult attention deficit hyperactivity disorder​
Project Manager: PD Dr. Maria Strauß
Project Duration: 2021 – 2026

PeriPREVENT – A contrast sparing strategy using automated Carbon Dioxide Injection during PERIpheral vascular interventions for PREVENTion of Major Adverse Kidney Events (MAKE)
Project Manager: Prof. Sabine Steiner​
Project Duration:​ 2023 – 2026


CARP-Studie – Cholangiocarcinoma treatment with radiofrequency ablation or photodynamic therapy 
Project Manager: Prof. Dr. med. Albrecht Hoffmeister
Project Duration: 202​2 – 2027



​MD-LEICS – Modern Diseases LEIpzig Clinician Scientist program MD-LEICS
Project Manager: Prof. Dr. Thomas Ebert
Project Duration: 2023 – 2027

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​MUC-FIRE – Does reducing the systematic enterostomy stool transfer after enterostomy placement reduce the time to complete enteral feeding after enterostomy reversal?
Project Manager: Prof. Dr. Martin Lacher 
Project Duration:  2017 – 2028



Find-AF2 – Inten​sive heart rhythm monitoring to decrease ischemic stroke and systemic embolism
Project Manager: Prof. Dr. Rolf Wachter 
Project Duration: 2019 – 2028

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International funding

Joint Projects with EU-funding over 500.000 Euro​​
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imSAVAR – Immune Safety Avatar: nonclinical mimicking of the immune system effects of immunomodulatory therapies 
Project Manager: Prof. Dr. Markus Löffler
Project Duration: 2019 – 2025

A-TANGO –​ Novel combinatorial treatment of acute-on-chronic liver failure
Project Manager: Prof. Dr. Thomas Berg
Project Duration: 2021 – 2026


CERTAINTY – A CEllulaR immunoTherapy virtuAl twin for personalIsed cancer treatmeNT
Project Manager:​ Prof. Dr. Thomas Neumuth​
Project Duration: 2023 – 2028​

ImmuneT - ME – Interrogation of the immune-microenvironment of T-cell malignancies
Project Manager:​ Prof. Marco Herling​
Project Duration: 2025 – 2028

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CREATIC – Central European Advanced Therapy and Immunotherapy Centre
Project Manager:​ Dr. Dr. Maik Friedrich​
Project Duration: 2023 – 2029

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European Research Council (ERC)

The following researchers of our faculty are funded with ERC Grants:

Prof. Dr. Stefan Hallermann
ERC Consolidator Grant – PreSynPlast - Molecular mechanisms of presynaptic plasticity
Project Duration​: 2020 – 2025


Prof. Dr. Ruth Stassart
ERC Starting Grant – AxoMyoGlia – Spatio-functional cellular interplay in peripheral nerve diseases
Project Duration: 2021 – 2025 

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Prof. Dr. Berend Isermann
ERC Advanced Grant – Targeting mechanisms of Thrombo-inflammation​
Project Duration: 2024 – 2029 

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Prof. Dr. Robert Fledrich
ERC Consolidator Grant – NERVADAPT –​ Metabolic adaptation in injuries of the peripheral nervous system
Project Duration: 2024 – 2029 

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International ​​Coalition for Epidemic Preparedness Innovations (CEPI)

The sponsor CEPI is an innovative global partnership committed to accelerating the development of vaccines against epidemic and pandemic threats.  

Computational Immunogen Design Pipeline​ – ​Establishment of a digital vaccine library using computer-aided vaccine development​
Project Manage​:​ Jun.-Prof. Dr. Clara T. Schoeder
Project Duration: 2023 – 2028 


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Federal Ministry of Education and Research

Project funding from the Federal Ministry of Education and Research makes a significant contribution to the research performance of our university. Our currently funded and recently completed projects with a funding amount of over 500,000 EUR are listed below:

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ELVIS – Nasal high-flow compared to non-invasive ventilation in treatment of acute acidotic hypercapnic exacerbation of chronic obstructive pulmonary disease 
Project Manager: Prof. Dr. med. Hubert Wirtz
Project Duration: 2020 – 2025

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SYMPATH – Systems Medicine of Pneumonia Aggravated Atherosclerosis​
Project Manager: Prof. Dr. Markus Scholz 
Project Duration: 2020 – 2025


6G-Health – ​High-performance 6G networking for distributed medical technology
Project Manager: Prof. Dr. Thomas Neumuth 
Project Duration: 2022 – 2025

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​​​FOMO – Nanoporous, form-fitting glass monoliths as drug depot systems for targeted drug delivery in dentistry 
Project Manager: PD Dr. rer. nat. Andreas König​ 
Project Duration: 2022 – 2025

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SMITH: Smart Medical Information Technology for Healthcare
Head of the Consortium​:  Prof. Dr. Markus Löffler 
Project Duration: 2016 – 2026


SMITH –​ Junior Research Group Development of a Terminology and Ontology-based Phenotyping Framework
Project Manager: Dr. Alexander Uciteli
Project Duration: 2021– 2026

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3MP-FUS – Neuromodulation in rare neuropsychiatric disorders with focused ultrasound
Project Manager: Prof. Dr. Andreas Melzer​
Project Duration: 2022 – 2026

COMPLETE NSTEMI – Complete revascularization versus culprit lesion only PCI in NSTEMI​
Project Manager: Univ.-Prof. Dr. med. Holger Thiele
Project Duration: 2022 – 2026​

INTERPOLAR_MI – The overarching Use Case of the Medical Informatics Initiative (MI-I) (Follow-up project from POLAR_MI): Reducing medication related problems and drug interactions
Project Manager: Prof. Dr. Markus Löffler
Project Duration: 2023 – 2026 

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​GeMTeX_MI – The overarching Use Case of the Medical Informatics Initiative (MI-I): Automatic indexing of medical texts for research​​  
Project Manager: Prof. Dr. Martin Boeker / Prof. Dr. Markus Löffler​ 
Project Duration: 2023 – 2026

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LE-REP – Leipzig Reproductive Health Research Center (Leipziger Zentrum für Reproduktionsmedizin)
Project Manager: Prof. Dr. Bahriye Aktas
Project Duration:​ 2023 – 2026


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ToSEE – Treatment of Established Status Epilepticus in the Elderly
Project Manager: Prof. Dr. Joseph Claßen 
Project Duration: 2018 – 2027



@ktivPLUS – Obesity and depression – development, acceptance, effectiveness, and cost-effectiveness of a self-help-enhancing online coach
Project Manager: Dr. rer. med. Margrit Löbner
Project Duration:​ 2022 –​ 2027

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LiSyM – LiSyM Cancer Collaborative Project - Early Detection and Prevention of Liver Cancer
Project Manager: Prof. Dr. Thomas Berg (SMART NAFLD Projekt)​
Project Druration: 2024 –202​7



DigitalHub DISTANCE:PRO – Project to link research and regional healthcare as part of the Medical Informatics Initiative: Optimizing patient care along the treatment pathway.
Project Manager: Prof. Dr. Gernot Marx
Project Duration: 2025 - 2027
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​​​NAKO – The German National Cohort:  To address research questions concerning a wide range of possible causes for major chronic diseases ​
Project Manager: Prof. Dr. Markus Löffler 
Project Duration: 2014 – 2028

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CARDIO-HOPE – Improving follow-up care after Hodgkin lymphoma
Project Manager: PD Dr. med. Magdalena Balcerek / Prof. Dr. med. Judith Gebauer​
Project Duration: 2026 – 2029


Federal Ministry for Economic Affairs and Climate Action

​MediNet – MediNet - Intelligent digital platform for the location- and time-independent medicine of the future
Project Manager: Prof. Dr. Thomas Neumuth​
Project Duration: 2022 – 2026

Saxon State Ministry of Science and Cultural Affairs

​Long Covid – Long-term effects of SARS-CoV-2 infection​
Project Manager​: Prof. Dr. Markus Löffler/Prof. Dr. Steffi Riedel-Heller
Project Duration​​: 2021 – 2025


​Transfer technologies – Transfer technologies – for the validation of protein and peptide therapeutics
Project Manager​: Jun.-Prof. Dr. Clara T. Schoeder​
Project Duration​​: 2024 – 2026​


KIMed – Network for Artificial Intelligence​
Project Manager​: Dr. Matthias Nüchter
Project Duration​​: 2025 – 2027 



Foundations

Foundations such as Deutsche Krebshilfe (German Cancer Aid) or the Volkswagen Foundation make a significant contribution to the promotion of our programs and projects. Our currently funded and recently completed projects with a funding amount of over 200,000 EUR are listed below:

Deutsche Krebshilfe


AML-CARE – Identification of somatic and psychosocial late effects and risk factors in AML long-term survivors as a basis for evidence-based follow-up care
Project Manager​: Prof. Dr. Klaus Metzeler
Project Duration:​ 2025 - 2028​


Hector-Stiftung

ISOLA – Identifying the optimal Sequence for bispecific antibodies and CAR T cells in multiple myeloma through single cell multi-omics
Project Manager​: Prof. Maximilian Merz / Dr. Kristin Reiche 
Project Duration: 2026​ – 2030


​José Carreras Stiftung

Decoding extramedullary myeloma disease using spatially resolved single sequencing
Project Manager​: Prof. Maximilian Merz / Dr. Kristin Reiche 
Project Duration​: 2023 – 2025

Interference in TCL1A-mediated signaling pathways of T-cell lymphocytic leukemias  
Project Manager​:​ Prof. Dr. Achim Aigner / Prof. Dr. Marco Herling 
Project Duration​: 2024 – 2027

Volkswagen Stiftung

Innovative Approaches to Antiviral Drug Development​ –​ Peptide-based crystallographic fragment screening for fast and efficient discovery of lead structures against zoonotic viral diseases
Project Participants: Prof. Jens Meiler, Prof. Norbert Sträter, Prof. Ralf Hoffmann
Project Duration: 2021 – 2024

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