Publikationen aus der Pharmakologie und Toxikologie

Bischof M, Olthoff S, Glas C, Thorn-Seshold O, Schaefer M, Hill K
TRPV3 endogenously expressed in murine colonic epithelial cells is inhibited by the novel TRPV3 blocker 26E01.
Cell Calcium 2020; 92: 102310
ISSN 0143-4160
Impact factor: 4.874
 
Dhein S
Different Effects of Cannabis Abuse on Adolescent and Adult Brain.
Pharmacology 2020; 105(11-12): 609-617
ISSN 0031-7012
Impact factor: 1.625
 
He JR, Yu SG, Tang Y, Illes P
Purinergic signaling as a basis of acupuncture-induced analgesia.
Purinergic Signal 2020; 16(3): 297-304
ISSN 1573-9538
Impact factor: 3.065
 
Illes P
P2X7 Receptors Amplify CNS Damage in Neurodegenerative Diseases.
Int J Mol Sci 2020; 21(17): 5996
ISSN 1422-0067
Impact factor: 4.556
 
Illes P, Rubini P, Ulrich H, Zhao Y, Tang Y
Regulation of Microglial Functions by Purinergic Mechanisms in the Healthy and Diseased CNS.
Cells 2020; 9(5): E1108
ISSN 2073-4409
Impact factor: 4.366
 
Illes P, Rubini P, Yin H, Tang Y
Impaired ATP Release from Brain Astrocytes May be a Cause of Major Depression.
Neurosci Bull 2020; 36(11): 1281-1284
ISSN 1673-7067
Impact factor: 4.326
 
Illes P, Verkhratsky A, Tang Y
Pathological ATPergic Signaling in Major Depression and Bipolar Disorder.
Front Mol Neurosci 2020; 12: 331
ISSN 1662-5099
Impact factor: 5.154
 
Illes P, Xu GY, Tang Y
Purinergic Signaling in the Central Nervous System in Health and Disease.
Neurosci Bull 2020; 36(11): 1239-1241
ISSN 1673-7067
Impact factor: 4.326
 
Langlhofer G, Schaefer N, Maric HM, Keramidas A, Zhang Y, Baumann P, Blum R, Breitinger U, Strømgaard K, Schlosser A, Kessels MM, Koch D, Qualmann B, Breitinger HG, Lynch JW, Villmann C
A Novel Glycine Receptor Variant with Startle Disease Affects Syndapin I and Glycinergic Inhibition.
J Neurosci 2020; 40(25): 4954-4969
ISSN 0270-6474
Impact factor: 5.673
 
Ren WJ, Ulrich H, Semyanov A, Illes P*, Tang Y*
TASK-3: New Target for Pain-Relief.
Neurosci Bull 2020; 36(8): 951-954
ISSN 1673-7067
Impact factor: 4.326
 
Salameh A, Zöbisch H, Schröder B, Vigelahn J, Jahn M, Abraham G, Seeger J, Dähnert I, Dhein S
Effects of Hypoxia and Acidosis on Cardiac Electrophysiology and Hemodynamics. Is NHE-Inhibition by Cariporide Still Advantageous?
Front Physiol 2020; 11: 224
ISSN 1664-042X
Impact factor: 3.367
 
Schaefer M, Kalwa H
Theoretical background of light-emitting diode total internal reflection fluorescence microscopy and photobleaching lifetime analysis of membrane-associated proteins-Part II.
J Biophotonics 2020; 13(4): e201960181
ISSN 1864-063X
Impact factor: 3.032
 
Sidorcenco V, Krahnen L, Schulz M, Remy J, Kögel D, Temme A, Krügel U, Franke H*, Aigner A*
Glioblastoma Tissue Slice Tandem-Cultures for Quantitative Evaluation of Inhibitory Effects on Invasion and Growth.
Cancers (Basel) 2020; 12(9): 2707
ISSN 2072-6694
Impact factor: 6.126
 
Tang Y, Illes P
Tribute to Prof. Geoffrey Burnstock: his contribution to acupuncture.
Purinergic Signal 2020; :
ISSN 1573-9538
Impact factor: bisher wurde noch kein IF ermittelt
Anmerkung des Referat Forschung: 02-2021 online ahead of print
 
Urban N, Schaefer M
Direct Activation of TRPC3 Channels by the Antimalarial Agent Artemisinin.
Cells 2020; 9(1): E202
ISSN 2073-4409
Impact factor: 4.366
 
Wenzel T, Buch T, Urban N, Weirauch U, Schierle K, Aigner A, Schaefer M, Kalwa H
Correction to: Restoration of MARCKS enhances chemosensitivity in cancer.
J Cancer Res Clin Oncol 2020; 146(4): 859-
ISSN 0171-5216
Impact factor: 3.656
 
Wenzel T, Büch T, Urban N, Weirauch U, Schierle K, Aigner A, Schaefer M, Kalwa H
Restoration of MARCKS enhances chemosensitivity in cancer.
J Cancer Res Clin Oncol 2020; 146(4): 843-858
ISSN 0171-5216
Impact factor: 3.656
 
Zhang Y, Huang L, Kozlov SA, Rubini P, Tang Y, Illes P
Acupuncture alleviates acid- and purine-induced pain in rodents.
Br J Pharmacol 2020; 177(1): 77-92
ISSN 0007-1188
Impact factor: 7.730

Gerndt S, Chen CC, Chao YK, Yuan Y, Burgstaller S, Scotto Rosato A, Krogsaeter E, Urban N, Jacob K, Nguyen ONP, Miller MT, Keller M, Vollmar AM, Gudermann T, Zierler S, Schredelseker J, Schaefer M, Biel M, Malli R, Wahl-Schott C, Bracher F, Patel S, Grimm C
Agonist-mediated switching of ion selectivity in TPC2 differentially promotes lysosomal function.
Elife 2020; 9: e54712
ISSN 2050-084X
Impact factor: 7.080
 
Glaser T, Andrejew R, Oliveira-Giacomelli A, Ribeiro DE, Bonfim Marques L, Ye Q, Ren WJ, Semyanov A, Illes P, Tang Y, Ulrich H
Purinergic Receptors in Basal Ganglia Diseases: Shared Molecular Mechanisms between Huntingtons and Parkinsons Disease.
Neurosci Bull 2020; 36(11): 1299-1314
ISSN 1673-7067
Impact factor: 4.326
 
Haange SB, Jehmlich N, Krügel U, Hintschich C, Wehrmann D, Hankir M, Seyfried F, Froment J, Hübschmann T, Müller S, Wissenbach DK, Kang K, Buettner C, Panagiotou G, Noll M, Rolle-Kampczyk U, Fenske W, von Bergen M
Gastric bypass surgery in a rat model alters the community structure and functional composition of the intestinal microbiota independently of weight loss.
Microbiome 2020; 8(1): 13
ISSN 2049-2618
Impact factor: 11.607
 
Kunz M, Brandl M, Bhattacharya A, Nobereit-Siegel L, Ewe A, Weirauch U, Hering D, Reinert A, Kalwa H, Guzman J, Weigelt K, Wach S, Taubert H, Aigner A
Nanoparticle-complexed antimiRs for inhibiting tumor growth and metastasis in prostate carcinoma and melanoma.
J Nanobiotechnology 2020; 18(1): 173
ISSN 1477-3155
Impact factor: 6.518
 
Kässner F, Kirstein A, Händel N, Schmid GL, Landgraf K, Berthold A, Tannert A, Schaefer M, Wabitsch M, Kiess W, Körner A, Garten A
A new human adipocyte model with PTEN haploinsufficiency.
Adipocyte 2020; 9(1): 290-301
ISSN 2162-3945
Impact factor: 3.146
 
Leser C, Keller M, Gerndt S, Urban N, Chen CC, Schaefer M, Grimm C, Bracher F
Chemical and pharmacological characterization of the TRPML calcium channel blockers ML-SI1 and ML-SI3.
Eur J Med Chem 2020; 0210: 112966
ISSN 0223-5234
Impact factor: 5.573
 
Panchal O, Wichmann G, Grenman R, Eckhardt L, Kunz-Schughart LA, Franke H, Dietz A, Aigner A
SATB1 as oncogenic driver and potential therapeutic target in head & neck squamous cell carcinoma (HNSCC).
Sci Rep 2020; 10(1): 8615
ISSN 2045-2322
Impact factor: 3.998
 
Peters A, Rabe P, Krumbholz P, Kalwa H, Kraft R, Schoneberg T, Staubert C
Natural biased signaling of hydroxycarboxylic acid receptor 3 and G protein-coupled receptor 84.
Cell Commun Signal 2020; 18(1): 31
ISSN 1478-811X
Impact factor: 4.344
 
Salameh A, Dhein S, Mewes M, Sigusch S, Kiefer P, Vollroth M, Seeger J, Dahnert I
Anti-oxidative or anti-inflammatory additives reduce ischemia/reperfusions injury in an animal model of cardiopulmonary bypass.
Saudi J Biol Sci 2020; 27(1): 18-29
ISSN 1319-562X
Impact factor: 2.820
 
Tang Y, Illes P, Verkhratsky A
Glial-neuronal Sensory Organs: Evolutionary Journey from Caenorhabditis elegans to Mammals.
Neurosci Bull 2020; 36(5): 561-564
ISSN 1673-7067
Impact factor: 4.326
 
Verkhratsky A, Zimmermann H, Abbracchio M, Illes P, DiVirgilio F
In Memoriam Geoffrey Burnstock: Creator of Purinergic Signaling
FUNCTION 2020; 1(1): 1-11
ISSN 2633-8823
Impact factor: 0.000​​

Belau F, Metzner K, Christ T, Ravens U, Schaefer M, Kunzel S, Li W, Wettwer E, Dobrev D, El-Armouche A, Kammerer S
DPP10 is a new regulator of Nav1.5 channels in human heart.
Int J Cardiol 2019; 284: 68-73
IF:    3.471

Feistkorn E, Greiner M, Desel H, Schaefer M, Graefe A, Franke H, Hahn A
[Health reporting of poisoning in Germany-a scientific investigation into the establishment of national poisoning monitoring in Germany : Background, preliminary work, requirements].
Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz 2019; 62(3): 341-349
ISSN 1436-9990
IF: 0.945

Franke H, Scholl R, Aigner A
Ricin and Ricinus communis in pharmacology and toxicology-from ancient use and "Papyrus Ebers" to modern perspectives and "poisonous plant of the year 2018".
Naunyn Schmiedebergs Arch Pharmacol 2019; 392(10): 1181-1208
IF:

Illes P, Rubini P, Huang L, Tang Y
The P2X7 receptor: a new therapeutic target in Alzheimer's disease.
Expert Opin Ther Targets 2019; 23(3): 165-176
IF:    4.621

Jungk L, Franke H, Salameh A, Dhein S
Golgi Fragmentation in Human Patients with Chronic Atrial Fibrillation: A New Aspect of Remodeling.
Thorac Cardiovasc Surg 2019; 67(2): 98-106
ISSN 0171-6425
IF: 1.152

Khan MT, Deussing J, Tang Y, Illes P
Astrocytic rather than neuronal P2X7 receptors modulate the function of the tri-synaptic network in the rodent hippocampus.
Brain Res Bull 2019; 151: 164-173
ISSN 0361-9230
IF: 3.103

Moldovan RP, Wenzel B, Teodoro R, Neumann W, Dukic-Stefanovic S, Kraus W, Rong P, Deuther-Conrad W, Hey-Hawkins E, Krugel U, Brust P
Studies towards the development of a PET radiotracer for imaging of the P2Y1 receptors in the brain: synthesis, 18F-labeling and preliminary biological evaluation.

Eur J Med Chem 2019; 165: 142-159
IF:    4.833

Feistkorn E, Greiner M, Desel H, Schaefer M, Graefe A, Franke H, Hahn A
[Health reporting of poisoning in Germany-a scientific investigation into the establishment of national poisoning monitoring in Germany : Background, preliminary work, requirements].
Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz 2019; 62(3): 341-349
IF:    

Jungk L, Franke H, Salameh A, Dhein S
Golgi Fragmentation in Human Patients with Chronic Atrial Fibrillation: A New Aspect of Remodeling.
Thorac Cardiovasc Surg 2019; 67(2): 98-106
IF:    

Obrecht AS, Urban N, Schaefer M, Rose A, Kless A, Meents JE, Lampert A, Abdelrahman A, Muller CE, Schmalzing G, Hausmann R
Identification of aurintricarboxylic acid as a potent allosteric antagonist of P2X1 and P2X3 receptors.
Neuropharmacology 2019; 158: 107749-
ISSN 0028-3908
IF:

Ondruschka B, Woydt L, Bernhard M, Franke H, Kirsten H, Loffler S, Pohlers D, Hammer N, Dressler J
Post-mortem in situ stability of serum markers of cerebral damage and acute phase response.
Int J Legal Med 2019; 133(3): 871-881
IF:   

Raudszus R, Nowotny R, Gertzen CGW, Scholer A, Krizsan A, Gockel I, Kalwa H, Gohlke H, Thieme R, Hansen FK
Fluorescent analogs of peptoid-based HDAC inhibitors: Synthesis, biological activity and cellular uptake kinetics.
Bioorg Med Chem 2019; 27(19): 115039
ISSN 0968-0896
IF: 2.802 

Tang Y, Yin HY, Liu J, Rubini P, Illes P
P2X receptors and acupuncture analgesia.
Brain Res Bull 2019; 151: 144-152
ISSN 0361-9230
IF: 3.103

Tang Y, Yin HY, Illes P, Burnstock G, Chen JF
From the Sino-German collaboration on purines to the Chinese Purine Club.
Purinergic Signal 2019; 15(3): 387-389
ISSN 1573-9538
IF:

Trautz F, Franke H, Bohnert S, Hammer N, Muller W, Stassart R, Tse R, Zwirner J, Dressler J, Ondruschka B
Survival-time dependent increase in neuronal IL-6 and astroglial GFAP expression in fatally injured human brain tissue.
Sci Rep 2019; 9(1): 11771
ISSN 2045-2322
IF:   ​​

Dhein S, Schmelmer K, Guenther J, Salameh A
Aspects of Methamphetamine Abuse in Adolescents and Young Adults in a Thuringian County.
Eur Addict Res 2018; 24(2): 98-105
IF: 2.653

Hafner S, Burg F, Kannler M, Urban N, Mayer P, Dietrich A, Trauner D, Broichhagen J, Schaefer M
A (+)-Larixol Congener with High Affinity and Subtype Selectivity toward TRPC6.
ChemMedChem 2018; 13(10): 1028-1035
IF: 3.009

Khan MT, Liu J, Nerlich J, Tang Y, Franke H, Illes P
Regulation of P2X7 receptor function of neural progenitor cells in the hippocampal subgranular zone by neuronal activity in the dentate gyrus.
Neuropharmacology 2018; 140: 139-149
IF: 4.249

Oberstadt M, Stieler J, Simpong DL, Romuss U, Urban N, Schaefer M, Arendt T, Holzer M
TDP-43 self-interaction is modulated by redox-active compounds Auranofin, Chelerythrine and Riluzole.
Sci Rep 2018; 8(1): 2248
IF: 4.122

Ondruschka B, Rosinsky F, Trauer H, Schneider E, Dressler J, Franke H
Drug- and/or trauma-induced hyperthermia? Characterization of HSP70 and myoglobin expression.
PLoS One 2018; 13(3): e0194442
IF: 2.766

Ondruschka B, Schuch S, Pohlers D, Franke H, Dressler J
Acute phase response after fatal traumatic brain injury.  
Int J Legal Med 2018; 132(2): 531-539
IF: 2.316

Ondruschka B, Sieber M, Kirsten H, Franke H, Dressler J
Measurement of Cerebral Biomarkers Proving Traumatic Brain Injuries in Post-Mortem Body Fluids.
J Neurotrauma 2018; 35(17): 2044-2055
IF: bisher wurde noch kein IF ermittelt

Picke AK, Campbell GM, Bluher M, Krugel U, Schmidt FN, Tsourdi E, Winzer M, Rauner M, Vukicevic V, Busse B, Salbach-Hirsch J, Tuckermann JP, Simon JC, Anderegg U, Hofbauer LC, Saalbach A
Thy-1 (CD90) promotes bone formation and protects against obesity.
Sci Transl Med 2018; 10(453): 1-12
IF: bisher wurde noch kein IF ermittelt

Salameh A, Schuster R, Dahnert I, Seeger J, Dhein S
Epigallocatechin Gallate Reduces Ischemia/Reperfusion Injury in Isolated Perfused Rabbit Hearts.
Int J Mol Sci 2018; 19(2): e628
IF: 3.687

Sieber M, Dressler J, Franke H, Pohlers D, Ondruschka B
Post-mortem biochemistry of NSE and S100B: A supplemental tool for detecting a lethal traumatic brain injury?
J Forensic Leg Med 2018; 55: 65-73
IF: 1.103

Stephan G, Huang L, Tang Y, Vilotti S, Fabbretti E, Yu Y, Norenberg W, Franke H, Goloncser F, Sperlagh B, Dopychai A, Hausmann R, Schmalzing G, Rubini P, Illes P
Author Correction: The ASIC3/P2X3 cognate receptor is a pain-relevant and ligand-gated cationic channel.
Nat Commun 2018; 9(1): 3351
IF: 12.353

Stephan G, Huang L, Tang Y, Vilotti S, Fabbretti E, Yu Y, Norenberg W, Franke H, Goroncser F, Sperlagh B, Dopychai A, Hausmann R, Schmalzing G, Rubini P, Illes P
The ASIC3/P2X3 cognate receptor is a pain-relevant and ligand-gated cationic channel.
Nat Commun 2018; 9(1): 1354
IF: 12.353

Wu D, Lee S, Luo J, Xia H, Gushchina S, Richardson PM, Yeh J, Krugel U, Franke H, Zhang Y, Bo X
Intraneural Injection of ATP Stimulates Regeneration of Primary Sensory Axons in the Spinal Cord.
J Neurosci 2018; 38(6): 1351-1365
IF: 5.970​​

Ewe A, Höbel S, Heine C, Merz L, Kallendrusch S, Bechmann I, Merz F, Franke H, Aigner A.
Optimized polyethylenimine (PEI)-based nanoparticles for siRNA delivery, analyzed in vitro and in an ex vivo tumor tissue slice culture model.
Drug Deliv Transl Res. 2017 Apr;7(2):206-216
IF:    

Gao P, Ding X, Khan TM, Rong W, Franke H, Illes P.
P2X7 receptor-sensitivity of astrocytes and neurons in the substantia gelatinosa of organotypic spinal cord slices of the mouse depends on the length of the culture period.
Neuroscience. 2017 May 4;349:195-207
IF:     3.277

Hankir MK, Patt M, Patt JT, Becker GA, Rullmann M, Kranz M, Deuther-Conrad W, Schischke K, Seyfried F, Brust P, Hesse S, Sabri O, Krügel U, Fenske WK.
Suppressed Fat Appetite after Roux-en-Y Gastric Bypass Surgery Associates with Reduced Brain μ-opioid Receptor Availability in Diet-Induced Obese Male Rats.
Front Neurosci. 2017 Jan 13;10:620
IF:   3.566

Hankir MK, Seyfried F, Hintschich CA, Diep TA, Kleberg K, Kranz M, Deuther-Conrad W, Tellez LA, Rullmann M, Patt M, Teichert J, Hesse S, Sabri O, Brust P, Hansen HS, de Araujo IE, Krügel U, Fenske WK.
Gastric Bypass Surgery Recruits a Gut PPAR-α-Striatal D1R Pathway to Reduce Fat Appetite in Obese Rats.
Cell Metab. 2017 Feb 7;25(2):335-344.
IF:   

Illes P, Khan TM, Rubini P.Neuronal P2X7 Receptors Revisited: Do They Really Exist?
J Neurosci. 2017 Jul 26;37(30):7049-7062.
IF:   

Illes P, Rubini P.
Regulation of neural stem/progenitor cell functions by P2X and P2Y receptors.
Neural Regen Res. 2017 Mar;12(3):395-396
IF:    1.769

Krügel U, Straub I, Beckmann H, Schaefer M.
Primidone inhibits TRPM3 and attenuates thermal nociception in vivo.
Pain. 2017 May;158(5):856-867
IF:       5.445

Merz L, Höbel S, Kallendrusch S, Ewe A, Bechmann I, Franke H, Merz F, Aigner A.
Tumor tissue slice cultures as a platform for analyzing tissue-penetration and biological activities of nanoparticles.
Eur J Pharm Biopharm 2017; 112: 45-50
IF:   

Moldovan RP, Els-Heindl S, Worm DJ, Kniess T, Kluge M, Beck-Sickinger AG, Deuther-Conrad W, Krügel U, Brust P.
Development of Fluorinated Non-Peptidic Ghrelin Receptor Ligands for Potential Use in Molecular Imaging.
Int J Mol Sci. 2017 Apr 5;18(4)
IF:    3.226

Oehler B, Kistner K, Martin C, Schiller J, Mayer R, Mohammadi M, Sauer RS, Filipovic MR, Nieto FR, Kloka J, Pflücke D, Hill K, Schaefer M, Malcangio M, Reeh PW, Brack A, Blum R, Rittner HL.
Inflammatory pain control by blocking oxidized phospholipid-mediated TRP channel activation.
Sci Rep. 2017 Jul 14;7(1):5447
IF:   

Rozmer K, Gao P, Araújo MG, Khan MT, Liu J, Rong W, Tang Y, Franke H, Krügel U, Fernandes MJ, Illes P.
Pilocarpine-Induced Status Epilepticus Increases the Sensitivity of P2X7 and P2Y1 Receptors to Nucleotides at Neural Progenitor Cells of the Juvenile Rodent Hippocampus.
Cereb Cortex. 2016 Jun 23. pii: bhw178. [Epub ahead of print]
IF:   

Salameh A, Keller M, Dähnert I, Dhein S.
Olesoxime Inhibits Cardioplegia-Induced Ischemia/Reperfusion Injury. A Study in Langendorff-Perfused Rabbit Hearts.^
Front Physiol. 2017 May 19;8:324
IF:    4.134

Spyra S, Meisner A, Schaefer M, Hill K.
COX-2-selective inhibitors celecoxib and deracoxib modulate TRPV3 channels.
Br J Pharmacol. 2017 Aug;174(16):2696-2705
IF:

Tang Y, Illes P
Regulation of adult neural progenitor cell functions by purinergic signaling.
Glia 2017; 65(2): 213-230
IF:    6.200

Wagner L, Pannicke T, Rupprecht V, Frommherz I, Volz C, Illes P, Hirrlinger J, Jägle H, Egger V, Haydon PG, Pfrieger FW, Grosche A.
Suppression of SNARE-dependent exocytosis in retinal glial cells and its effect on ischemia-induced neurodegeneration.
Glia. 2017 Jul;65(7):1059-1071
IF:   ​

Critical Evaluation of P2X7 Receptor Antagonists in Selected Seizure Models.
PLoS One. 2016 Jun 9;11(6):e0156468. doi: 10.1371/journal.pone.0156468. eCollection 2016.
IF:   3.057

Heine C, Sygnecka K, Franke H.
Purines in neurite growth and astroglia activation.
Neuropharmacology. 2016 May;104:255-71
IF:    4.936

Hill K, Fiorito S, Taddeo VA, Schulze A, Leonhardt M, Epifano F, Genovese S.
Plumbagin, Juglone, and Boropinal as Novel TRPA1 Agonists.
J Nat Prod. 2016 Apr 22;79(4):697-703
IF:    3.662

Illes P, Verkhratsky A, Burnstock G, Sperlagh B.
Purines in neurodegeneration and neuroregeneration.
Neuropharmacology. 2016 May;104:1-3 
No abstract available. 
IF:    4.936

Illes P, Verkhratsky A. 
Purinergic neurone-glia signalling in cognitive-related pathologies.
Neuropharmacology. 2016 May;104:62-75
IF:    4.936

Kaiser M, Penk A, Franke H, Krügel U, Nörenberg W, Huster D, Schaefer M.
Lack of functional P2X7 receptor aggravates brain edema development after middle cerebral artery occlusion
Purinergic Signal. 2016 Sep;12(3):453-63
IF:    3.196

Köles L, Kató E, Hanuska A, Zádori ZS, Al-Khrasani M, Zelles T, Rubini P, Illes P.
Modulation of excitatory neurotransmission by neuronal/glial signalling molecules: interplay between purinergic and glutamatergic systems.
Purinergic Signal. 2016 Mar;12(1):1-24.
IF:   3.196

Krügel U.
Purinergic receptors in psychiatric disorders.
Neuropharmacology. 2016 May;104:212-25
IF:   4.936

Machlus KR, Wu SK, Stumpo DJ, Soussou TS, Paul DS, Campbell RA, Kalwa H, Michel T, Bergmeier W, Weyrich AS, Blackshear PJ, Hartwig JH, Italiano JE Jr.
Synthesis and dephosphorylation of MARCKS in the late stages of megakaryocyte maturation drive proplatelet formation.
Blood. 2016 Mar 17;127(11):1468-80. 
IF:   11.861

Mayer MC, Schauenburg L, Thompson-Steckel G, Dunsing V, Kaden D, Voigt P, Schaefer M, Chiantia S, Kennedy TE, Multhaup G.
Amyloid precursor-like protein (APLP)1 exhibits stronger zinc-dependent neuronal adhesion than APP and APLP2.
J Neurochem. 2016 Apr;137(2):266-76
IF:    3.842

Nörenberg W, Plötz T, Sobottka H, Chubanov V, Mittermeier L, Kalwa H, Aigner A, Schaefer M.
TRPM7 is a molecular substrate of ATP-evoked P2X7-like currents in tumor cells.
J Gen Physiol. 2016 Jun;147(6):467-83
IF:   4.511

Oliveira Á, Illes P, Ulrich H.
Purinergic receptors in embryonic and adult neurogenesis.
Neuropharmacology. 2016 May;104:272-81
IF:    4.936

Salameh A, Dhein S, Dähnert I, Klein N.
Neuroprotective Strategies during Cardiac Surgery with Cardiopulmonary Bypass.
Int J Mol Sci. 2016 Nov 21;17(11).
IF:   3.257

Stephan G, Kowalski-Jahn M, Zens C, Schmalzing G, Illes P, Hausmann R.
Inter-subunit disulfide locking of the human P2X3 receptor elucidates ectodomain movements associated with channel gating.
Purinergic Signal. 2016 Jun;12(2):221-33.
IF:    3.196

Tang Y, Yin HY, Rubini P, Illes P
Acupuncture-Induced Analgesia: A Neurobiological Basis in Purinergic Signaling.
Neuroscientist. 2016 Dec;22(6):563-578.
IF:    7.295

Urban N, Wang L, Kwiek S, Rademann J, Kuebler WM, Schaefer M.
Identification and Validation of Larixyl Acetate as a Potent TRPC6 Inhibitor.
Mol Pharmacol. 2016 Jan;89(1):197-213.
IF:   3.931

Weyer M, Jahnke HG, Krinke D, Zitzmann FD, Hill K, Schaefer M, Robitzki AA.
Quantitative characterization of capsaicin-induced TRPV1 ion channel activation in HEK293 cells by impedance spectroscopy.
Anal Bioanal Chem. 2016 Nov;408(29):8529-8538.
IF:   3.125 ​

Bayer R, Franke H, Ficker C, Richter M, Lessig R, Büttner A, Weber M.
Alterations of neuronal precursor cells in stages of human adult neurogenesis in heroin addicts.
Drug Alcohol Depend. 2015 Nov 1;156:139-49. 
IF:    3.423    

Goede A, Dreßler J, Sommer G, Schober K, Franke H, Ondruschka B
Wundalterdiagnostik nach letalem Schädel-Hirn-Trauma.
Rechtsmedizin 2015; 25(4): 261-267
IF:    0.352

Hankir MK, Bronisch F, Hintschich C, Krügel U, Seyfried F, Fenske WK.
Differential effects of Roux-en-Y gastric bypass surgery on brown and beige adipose tissue thermogenesis.
Metabolism. 2015 Oct;64(10):1240-9
IF:    3.894

Heine C, Sygnecka K, Scherf N, Grohmann M, Bräsigk A, Franke H.
P2Y1 receptor mediated neuronal fibre outgrowth in organotypic co-cultures.
Neuropharmacology. 2015 Feb 13;93C:252-266
IF:   5.106    

Heine C, Sygnecka K, Franke H
Purines in neurite growth and astroglia activation
Neuropharmacology. 2016 May;104:255-71.
IF:    4.936

Kalwa H, Storch U, Demleitner J, Fiedler S, Mayer T, Kannler M, Fahlbusch M, Barth H, Smrcka A, Hildebrandt F, Gudermann T, Dietrich A.
Phospholipase C epsilon (PLCε) induced TRPC6 activation: a common but redundant mechanism in primary podocytes.
J Cell Physiol. 2015 Jun;230(6):1389-99
IF:    3.839 

Koch H, Bespalov A, Drescher K, Franke H, Krügel U.
Impaired Cognition after Stimulation of P2Y1 Receptors in the Rat Medial Prefrontal Cortex.
Neuropsychopharmacology. 2015 Jan;40(2):305-14
IF:    7.048

Kowalski M, Hausmann R, Schmid J, Dopychai A, Stephan G, Tang Y, Schmalzing G, Illes P, Rubini P.
Flexible subunit stoichiometry of functional human P2X2/3 heteromeric receptors.
Neuropharmacology. 2015 Dec;99:115-30. 
IF:   5.106

Krohn M, Dreßler J, Bauer M, Schober K, Franke H, Ondruschka B.
Immunohistochemical Investigation of S100 and NSE in Cases of Traumatic Brain Injury and Its Application for Survival Time Determination.
J Neurotrauma. 2015 Apr 1;32(7):430-440
IF:    3.714 

Krügel U.
Purinergic receptors in psychiatric disorders
Neuropharmacology. 2016 May;104:212-25
IF:   4.936

Oliveira Á, Illes P, Ulrich H.
Purinergic receptors in embryonic and adult neurogenesis
Neuropharmacology. 2016 May;104:272-81
IF:    4.936

Sygnecka K, Heine C, Scherf N, Fasold M, Binder H, Scheller C, Franke H.
Nimodipine enhances neurite outgrowth in dopaminergic brain slice co-cultures. 
Int J Dev Neurosci. 2015 Feb;40:1-11
IF:   2.580    

Sygnecka K, Heider A, Scherf N, Alt R, Franke H, Heine C. 
Mesenchymal Stem Cells Support Neuronal Fiber Growth in an Organotypic Brain Slice Co-culture Model.
Stem Cells Dev. 2015 Apr 1;24(7):824-35
IF:   3.727

Tabeling C, Yu H, Wang L, Ranke H, Goldenberg NM, Zabini D, Noe E, Krauszman A, Gutbier B, Yin J, Schaefer M, Arenz C, Hocke AC, Suttorp N, Proia RL, Witzenrath M, Kuebler WM.
CFTR and sphingolipids mediate hypoxic pulmonary vasoconstriction.
Proc Natl Acad Sci U S A. 2015 Mar 31;112(13):E1614-23
IF:    9.674   

Turnow K, Metzner K, Cotella D, Morales MJ, Schaefer M, Christ T, Ravens U, Wettwer E, Kämmerer S.
Interaction of DPP10a with Kv4.3 channel complex results in a sustained current component of human transient outward current Ito.
Basic Res Cardiol. 2015 Mar;110(2):5.
IF:    5.414

Wang L, Hagemann TL, Kalwa H, Michel T, Messing A, Feany MB.
Nitric oxide mediates glial-induced neurodegeneration in Alexander disease.
Nat Commun. 2015 Nov 26;6:8966
IF:   11.470

Chen CC, Keller M, Hess M, Schiffmann R, Urban N, Wolfgardt A, Schaefer M, Bracher F, Biel M, Wahl-Schott C, Grimm C.
A small molecule restores function to TRPML1 mutant isoforms responsible for mucolipidosis type IV.
Nat Commun. 2014 Aug 14;5:4681
IF:    10.742    

Christ T, Rozmaritsa N, Engel A, Berk E, Knaut M, Metzner K, Canteras M, Ravens U, Kaumann A.
Arrhythmias, elicited by catecholamines and serotonin, vanish in human chronic atrial fibrillation.
Proc Natl Acad Sci U S A. 2014 Jul 29;111(30):11193-8.
IF:    9.737

Colombo L, Parravicini C, Lecca D, Dossi E, Heine C, Cimino M, Wanke E, Illes P, Franke H, Abbracchio MP.
Ventral tegmental area/substantia nigra and prefrontal cortex rodent organotypic brain slices as an integrated model to study the cellular changes induced by oxygen/glucose deprivation and reperfusion: Effect of neuroprotective agents.
Neurochem Int. 2014 Jan;66:43-54. 
IF:    2.659

Ficker C, Rozmer K, Kató E, Andó RD, Schumann L, Krügel U, Franke H, Sperlágh B, Riedel T, Illes P.
Astrocyte-neuron interaction in the substantia gelatinosa of the spinal cord dorsal horn via P2X7 receptor-mediated release of glutamate and reactive oxygen species.
Glia. 2014 Oct;62(10):1671-86
IF:     5.066    

Fischer W, Urban N, Immig K, Franke H, Schaefer M.
Natural compounds with P2X7 receptor-modulating properties.
Purinergic Signal. 2014 Jun;10(2):313-26.
IF:     2.635

Franke H, Illes P.
Nucleotide signaling in astrogliosis.
Neurosci Lett. 2014 Apr 17;565:14-22
IF:    2.026

Franke H, Illes P.
Pathological potential of astroglial purinergic receptors.
Adv Neurobiol. 2014;11:213-56
IF:   

Graefe A, Müller R K, Franke H
Das Postgradualstudium "Toxikologie und Umweltschutz" an der Universität Leipzig - ein Vierteljahrhundert Toxikologie-Ausbildung
Toxichem Krimtech 2014; 81(2): 92-95
IF:

Hadamitzky M, Herring A, Keyvani K, Doenlen R, Krügel U, Bösche K, Orlowski K, Engler H, Schedlowski M.
Acute systemic rapamycin induces neurobehavioral alterations in rats.
Behav Brain Res. 2014 Oct 15;273:16-22
IF:       3.327

Heine C, Franke H.
Organotypic Slice Co-culture Systems to Study Axon Regeneration in the Dopaminergic System Ex Vivo.
Methods Mol Biol. 2014;1162:97-111.
IF:   

Kaiser M, Sobottka H, Fischer W, Schaefer M, Norenberg W.
Tanshinone II A sulfonate but not tanshinone II A acts as potent negative allosteric modulator of the human purinergic receptor P2X7.
J Pharmacol Exp Ther. 2014 Sep;350(3):531-42
IF:    3.891

Klein A, Tannert A, Schaefer M
Cholesterol sensitises the transient receptor potential channel TRPV3 to lower temperatures and activator concentrations.
Cell Calcium. 2014 Jan;55(1):59-68.
IF:    4.327

Koch H, Bespalov A, Drescher K, Franke H, Krügel U.
Impaired Cognition after Stimulation of P2Y1 Receptors in the Rat Medial Prefrontal Cortex.
Neuropsychopharmacology. 2015 Jan;40(2):305-14
IF:    8.678

Krohn M, Dressler J, Bauer M, Schober K, Franke H, Ondruschka B.
Immunohistochemical investigation of S100 and NSE in cases of traumatic brain injury (TBI) and its application for survival time determination.
J Neurotrauma. 2014 Sep 11. [Epub ahead of print]
IF:    3.968

Krügel U, Fischer J, Bauer K, Sack U, Himmerich H.
The impact of social isolation on immunological parameters in rats.
Arch Toxicol. 2014 Mar;88(3):853-5.
IF:    5.215

Mayer MC, Kaden D, Schauenburg L, Hancock MA, Voigt P, Roeser D, Barucker C, Than ME, Schaefer M, Multhaup G.
Novel Zinc-binding Site in the E2 Domain Regulates Amyloid Precursor-like Protein 1 (APLP1) Oligomerization.
J Biol Chem. 2014 Jul 4;289(27):19019-19030
IF:     4.651

Richter JM, Schaefer M, Hill K.
Riluzole activates TRPC5 channels independently of phospholipase C activity.
Br J Pharmacol. 2014 Jan;171(1):158-70
IF:    5.067

Richter JM, Schaefer M, Hill K.
Clemizole Hydrochloride is a Novel and Potent Inhibitor of Transient Receptor Potential Channel TRPC5.
Mol Pharmacol. 2014 Nov;86(5):514-21
IF:   4.120     

Richter M, Mewes A, Fritsch M, Krügel U, Hoffmann R, Singer D
Doubly Phosphorylated Peptide Vaccines to Protect Transgenic P301S Mice against Alzheimer's Disease Like Tau Aggregation
Vaccines 2014, 2(3), 601-623
IF:

Rubini P, Pagel G, Mehri S, Marquardt P, Riedel T, Illes P.
Functional P2X7 receptors at cultured hippocampal astrocytes but not neurons.
Naunyn Schmiedebergs Arch Pharmacol. 2014 Oct;387(10):943-54
IF:    2.147

Schaefer M
TRPs - modulation by drug-like compounds.
Handb Exp Pharmacol. 2014;223:1077-106
IF:    

Sperlágh B, Illes P.
P2X7 receptor: an emerging target in central nervous system diseases.
Trends Pharmacol Sci. 2014 Oct;35(10):537-47.
IF:

Schulze A, Hartung P, Schaefer M, Hill K  
Transient receptor potential ankyrin 1 (TRPA1) channel activation by the thienopyridine-type drugs ticlopidine, clopidogrel, and prasugrel.
Cell Calcium. 2014 Apr;55(4):200-7
IF:   4.327

Sygnecka K, Heine C, Scherf N, Fasold M, Binder H, Scheller C, Franke H.
Nimodipine enhances neurite outgrowth in dopaminergic brain slice co-cultures.
Int J Dev Neurosci. 2014 Nov 4;40C:1-11. doi: 10.1016/j.ijdevneu.2014.10.005. [Epub ahead of print]
IF:   

Sygnecka K, Heider A, Scherf N, Alt R, Franke H, Heine C.
Mesenchymal Stem Cells Support Neuronal Fiber Growth in an Organotypic Brain Slice Co-culture Model.
Stem Cells Dev. 2014 Nov 12. [Epub ahead of print]
IF:   

Abbracchio MP, Boeynaems JM, Cattaneo M, Di Virgilio F, Illes P, Inoue K, Jacobson KA, Teresa Miras-Portugal M, Ralevic V, Robson SC, Verkhratsky A, Zimmermann H.

Reply to: 'the discovery of a new class of synaptic transmitters in smooth muscle fifty years ago and amelioration of coronary artery thrombosis'.
Acta Physiol (Oxf). 2013 Jun;208(2):139-40
IF:    4.382     

Csölle C, Baranyi M, Zsilla G, Kittel A, Gölöncsér F, Illes P, Papp E, Vizi ES, Sperlágh B.
Neurochemical changes in the mouse hippocampus underlying the antidepressant effect of genetic deletion of P2X7 receptors.
PLoS One. 2013 Jun 21;8(6):e66547. 
IF:    3.730

Dossi E, Heine C, Servettini I, Gullo F, Sygnecka K, Franke H, Illes P, Wanke E.
Functional regeneration of the ex-vivo reconstructed mesocorticolimbic dopaminergic system.
Cereb Cortex. 2013 Dec;23(12):2905-22
IF:

Franke H, Parravicini C, Lecca D, Zanier ER, Heine C, Bremicker K, Fumagalli M, Rosa P, Longhi L, Stocchetti N, De Simoni MG, Weber M, Abbracchio MP.
Changes of the GPR17 receptor, a new target for neurorepair, in neurons and glial cells in patients with traumatic brain injury.
Purinergic Signal. 2013 Sep;9(3):451-62
IF:    2.635

Heine C, Sygnecka K, Scherf N, Berndt A, Egerland U, Hage T, Franke H.
Phosphodiesterase 2 inhibitors promote axonal outgrowth in organotypic slice co-cultures.
Cereb Cortex. 2013 Dec;23(12):2905-22
IF:    2.111    

Helms N, Kowalski M, Illes P, Riedel T.
Agonist antagonist interactions at the rapidly desensitizing P2X3 receptor.
PLoS One. 2013 Nov 1;8(11):e79213
IF:   

Hempel C, Nörenberg W, Sobottka H, Urban N, Nicke A, Fischer W, Schaefer M.
The phenothiazine-class antipsychotic drugs prochlorperazine and trifluoperazine are potent allosteric modulators of the human P2X7 receptor.
Neuropharmacology. 2013 Aug 14;75C:365-379
IF:   4.114     

Himmerich H, Fischer J, Bauer K, Kirkby KC, Sack U, Krügel U.
Stress-induced cytokine changes in rats.
Eur Cytokine Netw. 2013 Jun;24(2):97-103
IF:    1.896    

Illes P, Messemer N, Rubini P
P2Y receptors in neurogenesis
Wiley Interdisciplinary Reviews: Membrane Transport and Signaling
Volume 2, Issue 1, pages 43–48, January/February 2013

Jezierski S, Klein AS, Benz C, Schaefer M, Nagl S, Belder D.
Towards an integrated device that utilizes adherent cells in a micro-free-flow electrophoresis chip to achieve separation and biosensing.
Anal Bioanal Chem. 2013 Jun;405(16):5381-6.
IF:     3.778

Krügel U, Fischer J, Radicke S, Sack U, Himmerich H.
Antidepressant effects of TNF-α blockade in an animal model of depression.
J Psychiatr Res. 2013 May;47(5):611-6.
IF:    4.664

Leichsenring A, Riedel T, Qin Y, Rubini P, Illes P.
Anoxic depolarization of hippocampal astrocytes: Possible modulation by P2X7 receptors.
Neurochem Int. 2013 Jan;62(1):15-22
IF:     2.857 

Messemer N, Kunert C, Grohmann M, Sobottka H, Nieber K, Zimmermann H, Franke H, Nörenberg W, Straub I, Schaefer M, Riedel T, Illes P, Rubini P
P2X7 receptors at adult neural progenitor cells of the mouse subventricular zone.
Neuropharmacology. 2013 May 28;73C:122-137
IF:    4.114     

Ondruschka B, Pohlers D, Sommer G, Schober K, Teupser D, Franke H, Dressler J.
S100B and NSE as useful postmortem biochemical markers of traumatic brain injury in autopsy cases.
J Neurotrauma. 2013 Nov 15;30(22):1862-71
IF:   4.295     

Pacheco-López G, Doenlen R, Krügel U, Arnold M, Wirth T, Riether C, Engler A, Niemi MB, Christians U, Engler H, Schedlowski M.
Neurobehavioural activation during peripheral immunosuppression.
Int J Neuropsychopharmacol. 2013 Feb;16(1):137-49
IF:    4.578

Prager G, Hadamitzky M, Engler A, Doenlen R, Wirth T, Pacheco-López G, Krügel U, Schedlowski M, Engler H.
Amygdaloid signature of peripheral immune activation by bacterial lipopolysaccharide or staphylococcal enterotoxin B.
J Neuroimmune Pharmacol. 2013 Mar;8(1):42-50
IF:   3.802     

Radicke S, Riedel T, Cotella D, Turnow K, Ravens U, Schaefer M, Wettwer E.
Accessory subunits alter the temperature sensitivity of Kv4.3 channel complexes.
J Mol Cell Cardiol. 2013 Mar;56:8-18
IF:    5.166    

Schulze A, Oehler B, Urban N, Schaefer M, Hill K.
Apomorphine is a bimodal modulator of TRPA1 channels.
Mol Pharmacol. 2013 Feb;83(2):542-51
IF:    4.883

Straub I, Krugel U, Mohr F, Teichert J, Rizun O, Konrad M, Oberwinkler J, Schaefer M.
Flavanones that selectively inhibit TRPM3 attenuate thermal nociception in vivo.
Mol Pharmacol. 2013 Nov;84(5):736-50
IF:   4.411     

Straub I, Mohr F, Stab J, Konrad M, Philipp S, Oberwinkler J, Schaefer M.
Citrus fruit and fabacea secondary metabolites potently and selectively block TRPM3.
Br J Pharmacol. 2013 Apr;168(8):1835-50.
IF:    4.409    

Weber M, Scherf N, Kahl T, Braumann UD, Scheibe P, Kuska JP, Bayer R, Büttner A, Franke H.
Quantitative analysis of astrogliosis in drug-dependent humans.
Brain Res. 2013 Mar 15;1500:72-87
IF:    2.728    ​

Winkler U, Hirrlinger PG, Sestu M, Wilhelm F, Besser S, Zemljic-Harpf AE, Ross RS, Bornschein G, Krügel U, Ziegler WH, Hirrlinger J.
Deletion of the cell adhesion adaptor protein vinculin disturbs the localization of GFAP in Bergmann glial cells.
Glia. 2013 Jul;61(7):1067-83
IF:   4.820     

Bartolmäs T, Hirschfeld-Ihlow C, Jonas S, Schaefer M, Geßner R.
LI-cadherin cis-dimerizes in the plasma membrane Ca(2+) independently and forms highly dynamic trans-contacts.
Cell Mol Life Sci. 2012 Nov;69(22):3851-62. 
IF:    6.570

Cotella D, Radicke S, Cipriani V, Cavaletto M, Merlin S, Follenzi A, Ravens U, Wettwer E, Santoro C, Sblattero D. 
N-glycosylation of the mammalian dipeptidyl aminopeptidase-like protein 10 (DPP10) regulates trafficking and interaction with Kv4 channels.
Int J Biochem Cell Biol. 2012 Jun;44(6):876-85. 
IF:    4.634

Dossi E, Heine C, Servettini I, Gullo F, Sygnecka K, Franke H, Illes P, Wanke E.
Functional Regeneration of the ex-vivo Reconstructed Mesocorticolimbic Dopaminergic System.
Cereb Cortex. 2012 Sep 17. [published online: September 17, 2012]
IF:    6.544    

Franke H, Verkhratsky A, Burnstock G, Illes P. 
Pathophysiology of astroglial purinergic signalling.
Purinergic Signal. 2012 Sep;8(3):629-57. 
IF:    3.164     

Grabiec U, Koch M, Kallendrusch S, Kraft R, Hill K, Merkwitz C, Ghadban C, Lutz B, Straiker A, Dehghani F.
The endocannabinoid N-arachidonoyldopamine (NADA) exerts neuroprotective effects after excitotoxic neuronal damage via cannabinoid receptor 1 (CB(1)).
Neuropharmacology. 2012 Mar;62(4):1797-807. 
IF:    4.814     

Hausmann R, Bodnar M, Woltersdorf R, Wang H, Fuchs M, Messemer N, Qin Y, Gunther J, Riedel T, Grohmann M, Nieber K, Schmalzing G, Rubini P, Illes P.
ATP binding site mutagenesis reveals different subunit stoichiometry of functional P2X2/3 and P2X2/6 receptors. 
J Biol Chem. 2012 Apr 20;287(17):13930-43. 
IF:   4.773

Hellwig CT, Rehm M.
TRAIL Signaling and Synergy Mechanisms Used in TRAIL-Based Combination Therapies.
Mol Cancer Ther. 2012 Jan;11(1):3-13.
IF:    5.226     

Illes P, Verkhratsky A, Burnstock G, Franke H.
P2X Receptors and Their Roles in Astroglia in the Central and Peripheral Nervous System.
Neuroscientist. 2012 Oct;18(5):422-38. 
IF:    4.568

Kaden D, Harmeier A, Weise C, Munter LM, Althoff V, Rost BR, Hildebrand PW, Schmitz D, Schaefer M, Lurz R, Skodda S, Yamamoto R, Arlt S, Finckh U, Multhaup G.
Novel APP/Aβ mutation K16N produces highly toxic heteromeric Aβ oligomers.
EMBO Mol Med. 2012 Jul;4(7):647-59.
IF:   10.333

Klein AS, Schaefer M, Korte T, Herrmann A, Tannert A.
HaCaT keratinocytes exhibit a cholesterol and plasma membrane viscosity gradient during directed migration.
Exp Cell Res. 2012 Apr 15;318(7):809-18. 
IF:   3.580

Leichsenring A, Riedel T, Qin Y, Rubini P, Illes P.
Anoxic depolarization of hippocampal astrocytes: Possible modulation by P2X7 receptors.
Neurochem Int. 2012​ Nov 9. doi:pii: S0197-0186(12)00354-3. 10.1016/j.neuint.2012.11.002. [Epub ahead of print]

IF:    2.857

Meyer DK, Lindemeyer AK, Wilmes T, Sobottka H, Nörenberg W.
GluA and GluN receptors regulate the surface density of GluN receptor subunits in cultured neocortical interneurons.
J Neurochem. 2012 May;121(4):597-606
IF:    4.061

Mewes A, Franke H, Singer D.
Organotypic Brain Slice Cultures of Adult Transgenic P301S Mice-A Model for Tauopathy Studies.
PLoS One. 2012;7(9):e45017. 
IF:    4.092    

Nörenberg W, Kerstin Lindemeyer A, Wilmes T, Sobottka H, Meyer DK
Stimulation of GluN receptors decreases the surface density of GluN1/GluN2B subunits in cultured neocortical interneurons.
J Neurochem. 2012 May;121(4):587-96
IF:    4.061

Nörenberg W, Sobottka H, Hempel C, Plötz T, Fischer W, Schmalzing G, Schaefer M.
Positive allosteric modulation by ivermectin of human but not murine P2X7 receptors.
Br J Pharmacol. 2012 Sep;167(1):48-66
IF:   4.409

Oehler B, Scholze A, Schaefer M, Hill K.
TRPA1 is functionally expressed in melanoma cells but is not critical for impaired proliferation caused by allyl isothiocyanate or cinnamaldehyde.
Naunyn Schmiedebergs Arch Pharmacol. 2012 Jun;385(6):555-63. 
IF:    2.647     

Prager G, Hadamitzky M, Engler A, Doenlen R, Wirth T, Pacheco-López G, Krügel U, Schedlowski M, Engler H.
Amygdaloid Signature of Peripheral Immune Activation by Bacterial Lipopolysaccharide or Staphylococcal Enterotoxin B. 
J Neuroimmune Pharmacol. 2012 May 27. [published online: May 27, 2012]
IF:    3.528

Riedel T, Wiese S, Leichsenring A, Illes P.
Effects of Nucleotide Analogues at the P2X3 Receptor and its Mutants Identify the Agonist Binding Pouch.
Mol Pharmacol. 2012 Jul;82(1):80-9. 
IF:    4.883

Rossol M, Pierer M, Raulien N, Quandt D, Meusch U, Rothe K, Schubert K, Schöneberg T, Schaefer M, Krügel U, Smajilovic S, Bräuner-Osborne H, Baerwald C, Wagner U.
Extracellular Ca2+ is a danger signal activating the NLRP3 inflammasome through G protein-coupled calcium sensing receptors.
Nat Commun. 2012;3:1329. doi: 10.1038/ncomms2339.
IF:    7.396

Schulze A, Oehler B, Urban N, Schaefer M, Hill K.
Apomorphine is a bimodal modulator of TRPA1 channels.
Mol Pharmacol. 2012 Dec 6. [Epub ahead of print]
IF:    4.883

Staffa K, Ondruschka B, Franke H, Dressler J.
Cerebellar Gene Expression Following Human Traumatic Brain Injury (TBI).
J Neurotrauma 2012; 29(17): 2716-2721
IF:    3.654    

Straub I, Mohr F, Stab J, Konrad M, Philipp S, Oberwinkler J, Schaefer M.
Citrus fruit and fabacea secondary metabolites potently and selectively block TRPM3.
Br J Pharmacol. 2012 Nov 28. doi: 10.1111/bph.12076. [Epub ahead of print]
IF:    4.409    

Tautenhahn M, Leichsenring A, Servettini I, Pesic M, Sperlagh B, Nörenberg W, Illes P.
Purinergic modulation of the excitatory synaptic input onto rat striatal neurons.
Neuropharmacology. 2012 Mar;62(4):1756-66. 
IF:    4.814

Urban N, Hill K, Wang L, Kuebler WM, Schaefer M.
Novel pharmacological TRPC inhibitors block hypoxia-induced vasoconstriction.
Cell Calcium. 2012 Feb;51(2):194-206. 
IF:    3.766

Bodnar M, Wang H, Riedel T, Hintze S, Kato E, Fallah G, Groeger-Arndt H, Giniatullin R, Grohmann M, Hausmann R, Schmalzing G, Illes P, Rubini P.
Amino acid residues constituting the agonist binding site of the human P2X3 receptor.
J Biol Chem. 2011 Jan 28;286(4):2739-49.
IF: 5.328

Burnstock G, Krügel U, Abbracchio MP, Illes P.
Purinergic signalling: from normal behaviour to pathological brain function.
Prog Neurobiol. 2011 Oct;95(2):229-74. Epub 2011 Sep 1.
IF: 9,966

Doenlen R, Krügel U, Wirth T, Riether C, Engler A, Prager G, Engler H, Schedlowski M, Pacheco-López G.
Electrical activity in rat cortico-limbic structures after single or repeated administration of lipopolysaccharide or staphylococcal enterotoxin B.
Proc Biol Sci. 2011 Jun 22;278(1713):1864-72. Epub 2010 Nov 24.
IF: 5.064

Engel KM, Schrock K, Teupser D, Holdt LM, Tonjes A, Kern M, Dietrich K, Kovacs P, Krugel U, Scheidt HA, Schiller J, Huster D, Brockmann GA, Augustin M, Thiery J, Bluher M, Stumvoll M, Schoneberg T, Sc
Reduced Food Intake and Body Weight in Mice Deficient for the G Protein-Coupled Receptor GPR82.
PLoS One 2011; 6(12): e29400
IF: 4.411

Engler H, Doenlen R, Engler A, Riether C, Prager G, Niemi MB, Pacheco-López G, Krügel U, Schedlowski M.
Acute amygdaloid response to systemic inflammation.
Brain Behav Immun. 2011 Oct;25(7):1384-92. Epub 2011 Apr 18.
IF: 3.956

Franke H
Role of G protein-coupled receptors (GPCRs) for purines and pyrimidines in mediating degeneration and regeneration under neuroinflammatory processes.
Purinergic Signal. 2011 Mar;7(1):1-5.
IF: 2.975

Illes P, Verkhratsky A, Burnstock G, Franke H.
P2X ReceP2X Receptors and Their Roles in Astroglia in the Central and Peripheral Nervous System.ptors and Their Roles in Astroglia in the Central and Peripheral Nervous System.
Neuroscientist. 2011 Oct 19. [Epub ahead of print]
IF: 4.577

Klose C, Straub I, Riehle M, Ranta F, Krautwurst D, Ullrich S, Meyerhof W, Harteneck C
Fenamates as TRP channel blockers: mefenamic acid selectively blocks TRPM3.
Br J Pharmacol 2011; 162(8): 1757-1769
IF: 4.925

Koles L, Leichsenring A, Rubini P, Illes P
P2 receptor signaling in neurons and glial cells of the central nervous system.
Adv Pharmacol 2011; 61: 441-493
IF: 0.000

Kovacs FE, Illes P, Szabo B.
Purine receptor-mediated endocannabinoid production and retrograde synaptic signalling in the cerebellar cortex.
Br J Pharmacol. 2011 Feb;162(4):974-88
IF: 4.925

Kretzing S, Abraham G, Seiwert B, Ungemach FR, Krügel U, Regenthal R.
Dose-dependent emetic effects of the Amaryllidaceous alkaloid lycorine in beagle dogs.
Toxicon. 2011 Jan;57(1):117-24.
IF: 2.451

Kretzing S, Abraham G, Seiwert B, Ungemach FR, Krügel U, Teichert J, Regenthal R.
In vivo assessment of antiemetic drugs and mechanism of lycorine-induced nausea and emesis.
Arch Toxicol. 2011 Dec;85(12):1565-73. Epub 2011 May 31.
IF: 4.041

Lämmer AB, Beck A, Grummich B, Förschler A, Krügel T, Kahn T, Schneider D, Illes P, Franke H, Krügel U.
P2 Receptor Antagonist PPADS Supports Recovery from Experimental Stroke In Vivo.
The PLoS One. 2011;6(5):e19983. Epub 2011 May 17.
IF: 4.411

Noerenberg W, Hempel C, Urban N, Sobottka H, Illes P, Schaefer M.
Clemastine potentiates the human P2X7 receptor by sensitizing it to lower ATP concentrations.
J Biol Chem. 2011 Apr 1;286(13):11067-81
IF: 5.328

Oliveira JF, Riedel T, Leichsenring A, Heine C, Franke H, Krügel U, Nörenberg W, Illes P.
Rodent Cortical Astroglia Express In Situ Functional P2X7 Receptors Sensing Pathologically High ATP Concentrations.
Cereb Cortex. 2011 Apr;21(4):806-20.
IF: 6.844

Tremmel Ch, Azoitei A, Schaefer M, Hollmann H, Spindler-Barth M.
Influence of helix 12 of Ultraspiracle on Drosophila melanogaster ecdysone receptor function.
Insect Mol Biol. 2011 Aug;20(4):417-28. doi: 10.1111/j.1365-2583.2011.01077.x. Epub 2011 May 18.
IF: 2.669

Tremmel Ch, Schaefer M, Azoitei A, Ruff H, Spindler-Barth M.
Interaction of the N-terminus of ecdysone receptor isoforms with the ligand-binding domain.
Mol Cell Endocrinol. 2011 Jan 30;332(1-2):293-300. Epub 2010 Nov 20.
IF: 4.119

Wittenbrink N, Klein A, Weiser AA, Schuchhardt J, Or-Guil M
Is There a Typical Germinal Center? A Large-Scale Immunohistological Study on the Cellular Composition of Germinal Centers during the Hapten-Carrier-Driven Primary Immune Response in Mice.
J Immunol 2011; 187(12): 6185-6196
IF: 5.745

Wolf C, Rosefort C, Fallah G, Kassack MU, Hamacher A, Bodnar M, Wang H, Illes P, Kless A, Bahrenberg G, Schmalzing G, Hausmann R.
Molecular Determinants of Potent P2X2 Antagonism Identified by Functional Analysis, Mutagenesis and Homology Docking.
Mol Pharmacol. 2011 Apr;79(4):649-61
IF: 4.725

Arniges M, Fernández-Fernández JM, Albrecht N, Schaefer M, Valverde MA.
Human TRPV4 channel splice variants revealed a key role of ankyrin domains in multimerization and trafficking.
J Biol Chem. 2006 Jan 20;281(3):1580-6. Epub 2005 Nov 16. Erratum in: J Biol Chem. 2006 Mar 31;281(13):8996.

Balea IA, Illes P, Schober R
Affinity of corpora amylacea for oligonucleotides: sequence dependency and proteinaceous binding motif.
Neuropathology. 2006 Aug;26(4):277-82.

de Arriba SG, Krugel U, Regenthal R, Vissiennon Z, Verdaguer E, Lewerenz A, Garcia-Jorda E, Pallas M, Camins A, Munch G, Nieber K, Allgaier C.
Carbonyl stress and NMDA receptor activation contribute to methylglyoxal neurotoxicity.
Free Radic Biol Med. 2006 Mar 1;40(5):779-90.

Elsner A, Tarnow P, Schaefer M, Ambrugger P, Krude H, Grüters A, Biebermann H.
MC4R oligomerizes independently of extracellular cysteine residues.
Peptides. 2006 Feb;27(2):372-9. Epub 2005 Nov 9.

Franke H, Illes P.
Involvement of P2 receptors in the growth and survival of neurons in the CNS.
Pharmacol Ther. 2006 Mar;109(3):297-324.

Franke H, Krugel U, Illes P.
P2 receptors and neuronal injury.
Pflugers Arch. 2006 Aug;452(5):622-44.

Franke H, Grummich B, Hartig W, Grosche J, Regenthal R, Edwards RH, Illes P, Krugel U.
Changes in purinergic signaling after cerebral injury -- involvement of glutamatergic mechanisms?
Int J Dev Neurosci. 2006 Apr-May;24(2-3):123-32.

Garcia de Arriba S, Wegner F, Gruner K, Verdaguer E, Pallas M, Camins A, Wagner A, Wohlfahrt K, Allgaier C.
Different capacities of various NMDA receptor antagonists to prevent ischemia-induced neurodegeneration in human cultured NT2 neurons. Neurochem Int. 2006 Oct;49(5):466-74.

Gonzalez JB, Orth M, Schaefer M, Tauber R.
Endocytosis and intracellular trafficking of fatty acid esters of phenylaminopropanediol, the putative etiologic agents of the toxic oil syndrome (TOS).
Toxicol Lett. 2006 Jun 1;163(3):206-12. Epub 2005 Dec 15.

Hausmann R, Rettinger J, Gerevich Z, Meis S, Kassack MU, Illes P, Lambrecht G, Schmalzing G.
The suramin analog 4,4',4'',4'''-(carbonylbis(imino-5,1,3-benzenetriylbis (carbonylimino)))tetra-kis-benzenesulfonic acid (NF110) potently blocks P2X3 receptors: subtype selectivity is determined by location of sulfonic acid groups.
Mol Pharmacol. 2006 Jun;69(6):2058-67.

Heine C, Heimrich B, Vogt J, Wegner A, Illes P, Franke H.
P2 receptor-stimulation influences axonal outgrowth in the developing hippocampus in vitro.
Neuroscience. 2006;138(1):303-11.

Hill K, Tigue NJ, Kelsell RE, Benham CD, McNulty S, Schaefer M, Randall AD.
Characterisation of recombinant rat TRPM2 and a TRPM2-like conductance in cultured rat striatal neurones.
Neuropharmacology. 2006 Jan;50(1):89-97. Epub 2005 Nov 2.

Jaekel B, Muhlberg K, Garcia de Arriba S, Reichenbach A, Verdaguer E, Pallas M, Camins A, Norenberg W, Allgaier C.
Neuroprotection associated with alternative splicing of NMDA receptors in rat cortical neurons.
Br J Pharmacol. 2006 Mar;147(6):622-33.

Kittner H, Franke H, Harsch J, El-Ashmawy I.M., Seidel B, Krügel U, Illes P
Enhanced food intake after stimulation of hypothalamic P2Y1 receptors in rats: modulation of feeding behaviour by extracellular nucleotides
Eur J Neurosci. 2006 Oct;24(7):2049-56.

Lammer A, Gunther A, Beck A, Krugel U, Kittner H, Schneider D, Illes P, Franke H.
Neuroprotective effects of the P2 receptor antagonist PPADS on focal cerebral ischaemia-induced injury in rats.
Eur J Neurosci. 2006 May;23(10):2824-8.

Mager PP, Weber A, Sanchez L, Wirkner K, Illes P.
The monomers of the P2X1 receptor model and KcsA protein share a similar structural fold.
Protein Pept Lett. 2006 Jan;13(1):77-81.

Reither G, Schaefer M, Lipp P.
PKCalpha: a versatile key for decoding the cellular calcium toolkit.
J Cell Biol. 2006 Aug 14;174(4):521-33. Epub 2006 Aug 7.

Rittner HL, Labuz D, Schaefer M, Mousa SA, Schulz S, Schäfer M, Stein C, Brack A.
Pain control by CXCR2 ligands through Ca2+-regulated release of opioid peptides from polymorphonuclear cells.
FASEB J. 2006 Dec;20(14):2627-9. Epub 2006 Oct 23.

Rubini P, Pinkwart C, Franke H, Gerevich Z, Norenberg W, Illes P.
Regulation of intracellular Ca(2+) by P2Y(1) receptors may depend on the developmental stage of cultured rat striatal neurons.
J Cell Physiol. 2006; 209: 81 - 93.

Seidel B, Bigl M, Franke H, Kittner H, Kiess W, Illes P, Krugel U.
Expression of purinergic receptors in the hypothalamus of the rat is modified by reduced food availability.
Brain Res. 2006 May 17;1089(1):143-52.

Sperlagh B, Vizi ES, Wirkner K, Illes P.
P2X7 receptors in the nervous system.
Prog Neurobiol. 2006 Apr;78(6):327-46.

Schnell S, Schaefer M, Schöfl C.
Free fatty acids increase cytosolic free calcium and stimulate insulin secretion from beta-cells through activation of GPR40.
Mol Cell Endocrinol. 2007 Jan 15;263(1-2):173-80. Epub 2006 Nov 13.

Spencer JP, Weil A, Hill K, Hussain I, Richardson JC, Cusdin FS, Chen YH, Randall AD.
Transgenic mice over-expressing human beta-amyloid have functional nicotinic alpha 7 receptors.
Neuroscience. 2006 Feb;137(3):795-805. Epub 2005 Nov 21

Stanchev D, Flehmig G, Gerevich Z, Norenberg W, Dihazi H, Furst S, Eschrich K, Illes P, Wirkner K.
Decrease of current responses at human recombinant P2X3 receptors after substitution by Asp of Ser/Thr residues in protein kinase C phosphorylation sites of their ecto-domains.
Neurosci Lett. 2006 Jan 23;393(1):78-83.

Weber M, Modemann S, Schipper P, Trauer H, Franke H, Illes P, Geiger KD, Hengstler JG, Kleemann WJ.
Increased polysialic acid neural cell adhesion molecule expression in human hippocampus of heroin addicts.
Neuroscience. 2006;138(4):1215-23.

Wegierski T, Hill K, Schaefer M, Walz G.
The HECT ubiquitin ligase AIP4 regulates the cell surface expression of select TRP channels.
EMBO J. 2006 Dec 13;25(24):5659-69. Epub 2006 Nov 16.

Wirkner K, Gunther A, Weber M, Guzman SJ, Krause T, Fuchs J, Koles L, Norenberg W, Illes P.
Modulation of NMDA Receptor Current in Layer V Pyramidal Neurons of the Rat Prefrontal Cortex by P2Y Receptor Activation.
Cereb Cortex. 2006 Apr 28; [Epub ahead of print]

Voigt P, Dorner MB, Schaefer M.
Characterization of p87PIKAP, a novel regulatory subunit of phosphoinositide 3-kinase gamma that is highly expressed in heart and interacts with PDE3B.
J Biol Chem. 2006 Apr 14;281(15):9977-86. Epub 2006 Feb 13.

Alvira D, Tajes M, Verdaguer E, de Arriba SG, Allgaier C, Matute C, Trullas R, Jimenez A, Pallas M, Camins A
Inhibition of cyclin-dependent kinases is neuroprotective in 1-methyl-4-phenylpyridinium-induced apoptosis in neurons.
Neuroscience 2007; 146(1): 350-365.

Fischer W, Zadori Z, Kullnick Y, Gröger-Arndt H, Franke H, Wirkner K, Illes P, Mager PP.
Conserved lysin and arginin residues in the extracellular loop of P2X(3) receptors are involved in agonist binding.
Eur J Pharmacol. 2007 Dec 8;576(1-3):7-17.

Franke H, Schepper C, Illes P, Krügel U.
Involvement of P2X and P2Y receptors in microglial activation in vivo.
Purinergic Signal. 2007 Sep;3(4):435-45.

Gerevich Z, Zadori Z, Müller C, Wirkner K, Schröder W, Rubini P, Illes P.
Metabotropic P2Y receptors inhibit P2X3 receptor-channels via G protein-dependent facilitation of their desensitization.
Br J Pharmacol. 2007 May;151(2):226-36.

Gerevich Z, Zadori ZS, Köles L, Kopp L, Milius D, Wirkner K, Gyires K, Illes P.
Dual effect of acid pH on purinergic P2X3 receptors depends on the histidine 206 residue.
J Biol Chem. 2007 Nov 23;282(47):33949-57.

Heine C, Wegner A, Grosche J, Allgaier C, Illes P, Franke H.
P2 receptor expression in the dopaminergic system of the rat brain during development.
Neuroscience. 2007 Oct 12;149(1):165-81.

Hill K, Schaefer M.
TRPA1 is differentially modulated by the amphipathic molecules trinitrophenol and chlorpromazine.
J Biol Chem. 2007 Mar 9;282(10):7145-53.

Illes P.
Second Joint Italian-German Purine Club Meeting: "Progress in purinergic receptor pharmacology and function".
Purinergic Signal. 2007 Sep;3(4):247.

Karoly R, Mike A, Illes P, Gerevich Z.
The unusual state-dependent affinity of P2X3 receptors can be explained by an allosteric two-open-state model.
Mol Pharmacol. 2008 Jan;73(1):224-34.

Köles L, Gerevich Z, Oliveira JF, Zadori ZS, Wirkner K, Illes P.
Interaction of P2 purinergic receptors with cellular macromolecules.
Naunyn Schmiedebergs Arch Pharmacol. 2008 Mar;377(1):1-33.

Köles L, Fürst S, Illes P.
Purine ionotropic (P2X) receptors.
Curr Pharm Des. 2007;13(23):2368-84. Review

Milius D, Gröger-Arndt H, Stanchev D, Lange-Dohna C, Rossner S, Sperlagh B, Wirkner K, Illes P.
Oxygen/glucose deprivation increases the integration of recombinant P2X7 receptors into the plasma membrane of HEK293 cells.
Toxicology. 2007 Aug 16;238(1):60-9.

Munter LM, Voigt P, Harmeier A, Kaden D, Gottschalk KE, Weise C, Pipkorn R, Schaefer M, Langosch D, Multhaup G.
GxxxG motifs within the amyloid precursor protein transmembrane sequence are critical for the etiology of Abeta42.
EMBO J. 2007 Mar 21;26(6):1702-12.

Oliveira J, Ralton L, Tavares J, Codeiro-da-Silva A, Bestwick CS, McPherson A, Thoo Lin PK
The synthesis and the in vitro cytotoxicity studies of bisnaphthalimidopropyl polyamine derivatives against colon cancer cells and parasite Leishmania infantum.
Bioorg Med Chem 2007; 15(1): 541-545.

Plant TD, Zöllner C, Kepura F, Mousa SS, Eichhorst J, Schaefer M, Furkert J, Stein C, Oksche A.
Endothelin potentiates TRPV1 via ETA receptor-mediated activation of protein kinase C.
Mol Pain. 2007 3:35.

Rubini P, Engelhardt J, Wirkner K, Illes P.
Modulation by D1 and D2 dopamine receptors of ATP-induced release of intracellular Ca2+ in cultured rat striatal neurons.
Neurochem Int. 2008 Jan;52(1-2):113-8.

Semtner M, Schaefer M, Pinkenburg O, Plant TD.
Potentiation of TRPC5 by protons.
J Biol Chem. 2007 Nov 16;282(46):33868-78.

Schnell S, Schaefer M, Schöfl C.
Free fatty acids increase cytosolic free calcium and stimulate insulin secretion from beta-cells through activation of GPR40.
Mol Cell Endocrinol. 2007 Jan 15;263(1-2):173-80.

Sperlágh B, Illes P.
Purinergic modulation of microglial cell activation.
Purinergic Signal. 2007 Mar;3(1-2):117-27.

Sperlagh B, Zsilla G, Baranyi M, Illes P, Vizi ES
Purinergic modulation of glutamate release under ischemic-like conditions in the hippocampus.
Neuroscience 2007; 149(1): 99-111.

Szasz BK, Mike A, Karoly R, Gerevich Z, Illes P, Vizi ES, Kiss JP
Direct inhibitory effect of fluoxetine on N-methyl-d-aspartate receptors in the central nervous system.
Biol Psychiatry 2007; 62(11): 1303-1309.

Tannert A, Töpfer-Petersen E, Herrmann A, Müller K, Müller P.
The lipid composition modulates the influence of the bovine seminal plasma protein PDC-109 on membrane stability.
Biochemistry. 2007 Oct 16;46(41):11621-9.

Tannert A, Kurz A, Erlemann KR, Müller K, Herrmann A, Schiller J, Töpfer-Petersen E, Manjunath P, Müller P.
The bovine seminal plasma protein PDC-109 extracts phosphorylcholine-containing lipids from the outer membrane leaflet.
Eur Biophys J. 2007 Apr;36(4-5):461-75.

Wegner F, Rassler C, Allgaier C, Strecker K, Wohlfarth K
Auto-modulation of neuroactive steroids on GABA A receptors: a novel pharmacological effect.
Neuropharmacology 2007; 52(2): 672-683.

Wirkner K, Sperlagh B, Illes P.
P2X3 receptor involvement in pain states.
Mol Neurobiol. 2007 Oct;36(2):165-83.

Wirkner K, Günther A, Weber M, Guzman SJ, Krause T, Fuchs J, Köles L, Nörenberg W, Illes P.
Modulation of NMDA receptor current in layer V pyramidal neurons of the rat prefrontal cortex by P2Y receptor activation.
Cereb Cortex. 2007 Mar;17(3):621-31.

Frey D, Coelho V, Petrausch U, Schaefer M, Keilholz U, Thiel E, Deckert PM
Surface expression of gpA33 is dependent on culture density and cell-cycle phase and is regulated by intracellular traffic rather than gene transcription.
Cancer Biother Radiopharm. 2008; 23:65-73.

Karoly R, Mike A, Illes P, Gerevich Z
The unusual state-dependent affinity of P2X3 receptors can be explained by an allosteric two-open-state model.
Mol Pharmacol. 2008 Jan;73(1):224-34.

Köles L, Gerevich Z, Oliveira JF, Zadori ZS, Wirkner K, Illes P
Interaction of P2 purinergic receptors with cellular macromolecules.
Naunyn Schmiedebergs Arch Pharmacol. 2008 Mar;377(1):1-33.

Köles L, Gerevich Z, Kittner H, Krügel U, Franke H, Illes P.
Purinergic modulation of the brain dopaminergic transmission: behavioural pharmacologic conclusion.(Article in Hungarian). Neuropsychopharmacol Hung. 2008; 10(2);97-102

Milius D, Sperlagh B, Illes P.
Up-regulation of P2X7 receptor-immunoreactivity by in vitro ischemia on the plasma membrane of cultured rat cortical neurons.
Neurosci Lett. 2008 Nov 28;446(1):45-50.

Müller M, Essin K, Hill K, Beschmann H, Rubant S, Schempp CM, Gollasch M, Boehncke WH, Harteneck C, Müller WE, Leuner K.
Specific TRPC6 channel activation, a novel approach to stimulate keratinocyte differentiation.
J Biol Chem. 2008 Dec 5;283(49):33942-54. Epub 2008 Sep 25.

Oliveira JF, Krügel U, Köles L, Illes P, Wirkner K
Blockade of glutamate transporters leads to potentiation of NMDA receptor current in layer V pyramidal neurons of the rat prefrontal cortex via group II metabotropic glutamate receptor activation.
Neuropharmacology. 2008 Sep;55(4):447-53.

Rubini P, Engelhardt J, Wirkner K, Illes P
Abstract Modulation by D1 and D2 dopamine receptors of ATP-induced release of intracellular Ca(2+) in cultured rat striatal neurons.
Neurochem Int. 2008 Jan;52(1-2):113-8.

Pérez Sastre A, Grossmann S, Reusch HP, Schaefer M
Requirement of an Intermediate Gene Expression for Biphasic ERK1/2 Activation in Thrombin-stimulated Vascular Smooth Muscle Cells.
J Biol Chem. 2008 Sep 19;283(38):25871-8.

Schauwienold D, Pérez Sastre A, Genzel N, Schaefer M, Reusch HP
The transactivated EGF receptor recruits Pyk2 to regulate Src kinase activity.
J Biol Chem. 2008 Oct 10;283(41):27748-56.

Scherf N., Heine C., Braumann U.D., Kuska J.P., Franke H.
Segmentation of axonal fibres in histological sections. In: T. Tolxdorff (Hrsg.) Bildverabeitung für die Medizin, Algorithmen-Systeme-Anwendungen, Springer-Verlag, Berlin-Heidelberg.
178-182.

Tannert A, Voigt P, Burgold S, Tannert S, Schaefer M
Signal amplification between Gbetagamma release and PI3Kgamma-mediated PI(3,4,5)P3 formation monitored by a fluorescent Gbetagamma biosensor protein and repetitive two component total internal reflection/fluorescence redistribution after photobleaching analysis. Biochemistry 2008 Oct 28;47(43):11239-50.

Pinto E, Queiroz MJ, Vale-Silva LA, Oliveira JF, Begouin A, Begouin JM, Kirsch G
Antifungal activity of synthetic di(hetero)arylamines based on the benzo[b]thiophene moiety.
Bioorg Med Chem. 2008 Sep 1;16(17):8172-7.

Kaden D, Munter LM, Joshi M, Treiber C, Weise C, Bethge T, Voigt P, Schaefer M, Beyermann M, Reif B, Multhaup G
Homophilic interactions of the amyloid precursor protein (APP) ectodomain are regulated by the loop region and affect beta-secretase cleavage of APP.
J Biol Chem 2008; 283:7271-7279

Wirkner K, Stanchev D, Milius D, Hartmann L, Kato E, Zadori ZS, Mager PP, Rubini P, Nörenberg W, Illes P.
Regulation of the pH sensitivity of human P2X receptors by N-linked glycosylation.
J Neurochem. 2008 Dec;107(5):1216-24. 

De Petrocellis L, Deva R, Mainieri F, Schaefer M, Bisogno T, Ciccoli R, Ligresti A, Hill K, Nigam S, Appendino G, Di Marzo V.
Chemical synthesis, pharmacological characterization, and possible formation in unicellular fungi of 3-hydroxy-anandamide.
J Lipid Res. 2009 Apr;50(4):658-66. Epub 2008 Nov 17.

Dorner BG, Dorner MB, Zhou X, Opitz C, Mora A, Güttler S, Hutloff A, Mages HW, Ranke K, Schaefer M, Jack RS, Henn V, Kroczek RA.
Selective expression of the chemokine receptor XCR1 on cross-presenting dendritic cells determines cooperation with CD8+ T cells.
Immunity. 2009 Nov 20;31(5):823-33. Epub 2009 Nov 12.

Fischer W, Appelt K, Grohmann M, Franke H, Nörenberg W, Illes P
Increase of intracellular Ca2+ by P2X and P2Y receptor-subtypes in cultured cortical astroglia of the rat.
Neuroscience. 2009 Jun 2;160(4):767-83. Epub 2009 Mar 13.

Fischer W, Nörenberg W, Franke H, Schaefer M, Illes P.
Increase of intracellular Ca2+ by P2Y but not P2X receptors in cultured cortical multipolar neurons of the rat.
J Comp Neurol. 2009 Oct 10;516(5):343-59.

Franke H, Sauer C, Rudolph C, Krügel U, Hengstler JG, Illes P.
P2 receptor-mediated stimulation of the PI3-K/Akt-pathway in vivo.
Glia. 2009 Aug 1;57(10):1031-45.

Grossmann S, Higashiyama S, Oksche A, Schaefer M, Tannert A.
Localisation of endothelin B receptor variants to plasma membrane microdomains and its effects on downstream signalling.
Mol Membr Biol. 2009 Aug;26(5):279-92.

Hill K, Schaefer M.
Ultraviolet light and photosensitising agents activate TRPA1 via generation of oxidative stress.
Cell Calcium. 2009 Feb;45(2):155-64. Epub 2008 Sep 23.

Kaden D, Voigt P, Munter LM, Bobowski KD, Schaefer M, Multhaup G.
Subcellular localization and dimerization of APLP1 are strikingly different from APP and APLP2.
J Cell Sci. 2009 Feb 1;122(Pt 3):368-77. Epub 2009 Jan 6.

Kofler M, Schuemann M, Merz C, Kosslick D, Schlundt A, Tannert A, Schaefer M, Luhrmann R, Krause E, Freund C.
Proline-rich sequence recognition I: Marking GYF and WW domain assembly sites in early spliceosomal complexes.
Mol Cell Proteomics. 2009 Nov;8(11):2461-73. Epub 2009 May 30.

Kurig B, Shymanets A, Bohnacker T, Prajwal, Brock C, Ahmadian MR, Schaefer M, Gohla A, Harteneck C, Wymann MP, Jeanclos E, Nurnberg B
Ras is an indispensable coregulator of the class IB phosphoinositide 3-kinase p87/p110gamma.
Proc Natl Acad Sci U S A. 2009 Dec 1;106(48):20312-7. Epub 2009 Nov 11.
ISSN 1091-6490

Pissarek M, Meyer-Kirchrath J, Hohlfeld T, Vollmar S, Oros-Peusquens AM, Flögel U, Jacoby C, Krügel U, Schramm N.
Targeting murine heart and brain: visualisation conditions for multi-pinhole SPECT with (99m)Tc- and (123)I-labelled probes.
Eur J Nucl Med Mol Imaging. 2009 Sep;36(9):1495-509. Epub 2009 May 7.

Regenthal R, Koch H, Köhler C, Preiss R, Krügel U.
Depression-like deficits in rats improved by subchronic modafinil.
Psychopharmacology (Berl). 2009 Jul;204(4):627-39. Epub 2009 Mar 3.

Rittner HL, Hackel D, Voigt P, Mousa S, Stolz A, Labuz D, Schäfer M, Schaefer M, Stein C, Brack A.
Mycobacteria attenuate nociceptive responses by formyl peptide receptor triggered opioid peptide release from neutrophils.
PLoS Pathog. 2009 Apr;5(4):e1000362. Epub 2009 Apr 3.

Rubini P, Milosevic J, Engelhardt J, Al-Khrasani M, Franke H, Heinrich A, Sperlagh B, Schwarz SC, Schwarz J, Nörenberg W, Illes P.
Increase of intracellular Ca2+ by adenine and uracil nucleotides in human midbrain-derived neuronal progenitor cells.
Cell Calcium. 2009 May;45(5):485-98. Epub 2009 Apr 21.

Stanchev D, Blosa M, Milius D, Gerevich Z, Rubini P, Schmalzing G, Eschrich K, Schaefer M, Wirkner K, Illes P.
Cross-inhibition between native and recombinant TRPV1 and P2X(3) receptors.
Pain. 2009 May;143(1-2):26-36. Epub 2009 Feb 14.

Tannert A, Tannert S, Burgold S, Schaefer M.
Convolution-based one and two component FRAP analysis: theory and application.
Eur Biophys J. 2009 Jun;38(5):649-61. Epub 2009 Feb 24.

Treiber C, Quadir MA, Voigt P, Radowski M, Xu S, Munter LM, Bayer TA, Schaefer M, Haag R, Multhaup G.
Cellular copper import by nanocarrier systems, intracellular availability, and effects on amyloid beta peptide secretion.
Biochemistry. 2009 May 26;48(20):4273-84.

Andó RD, Méhész B, Gyires K, Illes P, Sperlágh B.
A comparative analysis of the activity of ligands acting at P2X and P2Y receptor subtypes in models of neuropathic, acute and inflammatory pain.
Br J Pharmacol. 2010 Mar;159(5):1106-17.
IF: 5.204

Bachem A, Güttler S, Hartung E, Ebstein F, Schaefer M, Tannert A, Salama A, Movassaghi K, Opitz C, Mages HW, Henn V, Kloetzel PM, Gurka S, Kroczek RA.
Superior antigen cross-presentation and XCR1 expression define human CD11c+CD141+ cells as homologues of mouse CD8+ dendritic cells.
J Exp Med. 2010 Jun 7;207(6):1273-81.
IF: 14.505

Cotella D, Radicke S, Bortoluzzi A, Ravens U, Wettwer E, Santoro C, Sblattero D.
Impaired glycosylation blocks DPP10 cell surface expression and alters the electrophysiology of Ito channel complex.
Pflugers Arch. 2010 Jun;460(1):87-97.
IF: 3.695

Guzman SJ, Schmidt H, Franke H, Krügel U, Eilers J, Illes P, Gerevich Z.
P2Y(1) receptors inhibit long-term depression in the prefrontal cortex.
Neuropharmacology. 2010 Nov;59(6):406-15.
IF: 3.909

Illes P, Schrör K
Neue Antiparkinsonmittel
Biospektrum 2010; 4: 464

Khakpay R, Polster D, Köles L, Skorinkin A, Szabo B, Wirkner K, Illes P.
Potentiation of the glutamatergic synaptic input to rat locus coeruleus neurons by P2X7 receptors.
Purinergic Signal. 2010 Sep;6(3):349-59.
IF: 2.870

Nörenberg W, Schunk J, Fischer W, Sobottka H, Riedel T, Oliveira JF, Franke H, Illes P.
Electrophysiological classification of P2X7 receptors in rat cultured neocortical astroglia.
Br J Pharmacol. 2010 Aug;160(8):1941-52.
IF: 5.204

Salameh A, Wustmann A, Karl S, Blanke K, Apel D, Rojas-Gomez D, Franke H, Mohr FW, Janousek J, Dhein S.
Cyclic Mechanical Stretch Induces Cardiomyocyte Orientation and Polarization of the Gap Junction Protein Connexin43.
Circ Res. 2010 May 28;106(10):1592-602.
IF: 9.214

Schöneberg T., Illes P., Burnstock G
The German Research Unit "Neuronal and glial P2 receptors; molecular basis and functional significance"
Purinergic Signal. 2010 Jun;6(2):285-7.
IF: 2.870

Wurm A, Lipp S, Pannicke T, Linnertz R, Krügel U, Schulz A, Färber K, Zahn D, Grosse J, Wiedemann P, Chen J, Schöneberg T, Illes P, Reichenbach A, Bringmann A.
Endogenous purinergic signaling is required for osmotic volume regulation of retinal glial cells.
J Neurochem. 2010 Mar;112(5):1261-72.
IF: 3.999​