The Paul Flechsig Institute has a wide range of methods at its disposal that are used in neuroscientific research. These methods are used to investigate the neural basis of pathological processes, both in the brain and in peripheral neural tissues, thereby gaining comprehensive insight into their functioning.
An integral part of the institute's range of methods is the imaging and histological processing of nerve tissue. Various state-of-the-art high-resolution microscopes enable the visualization of smallest tissue structures up to the three-dimensional reconstruction of entire cells or cell clusters. This makes it possible to visualise changes in the brain and nerve tissue and is therefore a valuable tool for investigating fundamental neural processes.
In addition, the Paul Flechsig Institute uses a variety of other methods, ranging from basic molecular biology methods and in vitro experiments to advanced protein biochemical analyses such as enzyme kinetics and flow cytometry. There is an increasing focus on gene expression analyses at the single-cell level, which can provide insights into the interaction and activity of different cells.
The Paul Flechsig Institute also has an animal laboratory for behavioural biology, where analytical methods of learning and memory research are applied.