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Prof. Dr. Carmine Maria Pariante, MD, FRCPsych, PhD

Research focus

  • Depression treatment and pathophysiology
  • Perinatal and maternal mental health
  • Stress, inflammation and mental disorders
  • Biomarkers and personalized psychiatry
  • Cellular models of depression

​Official position 

Professor in Biological Psychiatry and Head of Section

Institution 

Institute of Psychiatry, Psychology and Neuroscience (IoPPN), King’s College London

Business address 

G.32.01, The Maurice Wohl Clinical Neuroscience Institute, Cutcombe Road, London, SE5 9RT, United Kingdom

Academic education and degrees

1990

​MD in Medicine and Surgery, Cum Laude
Gemelli University School of Medicine, Rome, Italy

​1994

Specialist in Psychiatry, Cum Laude, University of Cagliari, Italy

​1999

MRCPsych, Royal College of Psychiatry, London; Section 12 approval

​2003

​PhD, University of London

​2004

​Certificate of Completion of Specialist Training in General Adult Psychiatry
Endorsement in Liaison Psychiatry, London Deanery, UK

​2013

​FRCPsych, Royal College of Psychiatry, London

 

Professional career

​1991 - 1994

Trainee in Psychiatry, University of Cagliari, Italy

​1995 - 1997

Research Fellow in Biological Psychiatry, Department of Psychiatry and Behavioral Sciences, Emory University, Atlanta, GA, USA

​1997 - 1999

Senior House Officer in Psychiatry, Maudsley Hospital, London

​1999 - 2002

Medical Research Council Clinical Training Fellow, Institute of Psychiatry, London

​2002 - 2004

Clinical Lecturer, Institute of Psychiatry, London

​2004 - 2007

Senior Clinical Lecturer, Institute of Psychiatry, London

​2004 - 2009

Medical Research Council Clinician Scientist, Institute of Psychiatry, London

​2007 - 2012

Reader in Biological Psychiatry and Head of Section, Institute of Psychiatry, London

​Current

​Professor in Biological Psychiatry and Head of Section, Institute of Psychiatry, Psychology and Neuroscience (IoPPN), King's College London (from 1st April 2012)

​Current

NIHR Senior Investigator (from 1st of April 2017)

​Current

​Consultant in the Perinatal Psychiatry Liaison Services, King's College Hospital & South London and Maudsley NHS Trust (from 1st of August 2008)

 

Honors, awards and positions

2002

British Association for Psychopharmacology & Vernalis Annual Prize

​2003, 2005

NARSAD Young Investigator Award

​2003

International Society of Psychoneuroendocrinology “Curt Richter Award”

​2007

Young Minds in Psychiatry Award by the American Psychiatric Institute

​2009

British Association for Psychopharmacology Senior Psychopharmacology Award

​2012

Academic Psychiatrist of the Year by the Royal College of Psychiatrists, UK

​2013

British Association for Psychopharmacology Public Communication Award

​2015

Anna-Monika Foundation Prize

​2016

Psychoneuroimmunology Research Society ‘Norman Cousins Award’

​2017

Parent Infant (PIP UK) Award for Outstanding Contribution to Infant Mental Health

​2017

NARSAD Distinguished Investigator Award

​2017 - 2025

NIHR Senior Investigator

​2018

Art of Neuroscience Award, Royal Academy of Arts and Sciences (The Netherlands)

​2018 - 2028

​Editor in Chief Brain, Behavior & Immunity

​2018, 2019

Clarivate Analytics Highly Cited Researchers 

​2019 - present

Anna-Monika Foundation Prize Committee of Judges

​2020 - 2023

President, International Society for Psychoneuroendocrinology (ISPNE)

​2020

Strategic Advisory Board, Wellcome Trust Mental Health Programme

 

Current journal editorial positions

​2018 - 2028

Editor in Chief Brain, Behavior & Immunity

​Editorial board

Molecular Psychiatry, Translational Psychiatry, Psychoneuroendocrinology, Biological Psychiatry

 

10 most important peer-reviewed papers (10 out of: 372, SCOPUS h-index: 78)

  1. Borsini A, Di Benedetto MG, Giacobbe J, Pariante CM. Pro- and anti-inflammatory properties of interleukin (IL6) in vitro: relevance for major depression and for human hippocampal neurogenesis [published online ahead of print, 2020 Jul 29]. Int J Neuropsychopharmacol. 2020;pyaa055.

  2. Nettis MA, Veronese M, Nikkheslat N, Mariani N, Lombardo G … Pariante CM. PET imaging shows no changes in TSPO brain density after IFN-α immune challenge in healthy human volunteers. Transl Psychiatry. 2020;10(1):89.

  3. Sawyer KM, Zunszain PA, Dazzan P, Pariante CM. Intergenerational transmission of depression: clinical observations and molecular mechanisms. Mol Psychiatry. 2019;24(8):1157-1177.

  4. Otte C, Gold SM, Penninx BW, Pariante CM, Etkin A et al. Major depressive disorder. Nat Rev Dis Primers. 2016;2:16065.

  5. Cattaneo A, Cattane N, Malpighi C, Czamara D, Suarez A … Pariante CM. FoxO1, A2M, and TGF-β1: three novel genes predicting depression in gene X environment interactions are identified using cross-species and cross-tissues transcriptomic and miRNomic analyses. Mol Psychiatry. 2018;23(11):2192-2208.

  6. Chamberlain SR, Cavanagh J, de Boer P, Mondelli V, Jones DN … Pariante CM et al. Treatment-resistant depression and peripheral C-reactive protein. Br J Psychiatry. 2019;214(1):11-19.

  7. Osborne S, Biaggi A, Chua TE, Du Preez A, Hazelgrove K … Pariante CM. Antenatal depression programs cortisol stress reactivity in offspring through increased maternal inflammation and cortisol in pregnancy: The Psychiatry Research and Motherhood - Depression (PRAM-D) Study. Psychoneuroendocrinology. 2018;98:211-221.

  8. Russell A, Hepgul N, Nikkheslat N, Borsini A, Zajkowska Z … Pariante CM. Persistent fatigue induced by interferon-alpha: a novel, inflammation-based, proxy model of chronic fatigue syndrome. Psychoneuroendocrinology. 2019;100:276-285.

  9. Cattaneo A, Ferrari C, Turner L, Mariani N, Enache D … Pariante CM. Whole-blood expression of inflammasome- and glucocorticoid-related mRNAs correctly separates treatment-resistant depressed patients from drug-free and responsive patients in the BIODEP study. Transl Psychiatry. 2020;10(1):232.

  10. Pariante CM. Why are depressed patients inflamed? A reflection on 20 years of research on depression, glucocorticoid resistance and inflammation. Eur Neuropsychopharm. 2017;27(6),554-559.

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04103 Leipzig
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