Language and Aphasia Lab

• Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig
• Day-clinic for Cognitive Neurology, University of Leipzig Medical Centre
• Department of Neuroradiology, University of Leipzig Medical Centre
• Department for Image and Signal Processing, Institute of Computer Science, University Leipzig
• Cognitive and Biological Psychology​, University Leipzig​​​

Current publication lists are available via the ORCID-IDs of the working group members

Key publications of the working group (File​)

1. ​Saur D, Lange R, Baumgaertner A, Schraknepper V, Willmes K, Rijntjes M, Weiller C. Dynamics of language reorganization after stroke. Brain 2006; 129:1371-1384. https://doi.org/10.1093/brain/awl090
   
   
2. Saur D, Kreher BW, Schnell S, Kümmerer D, Kellmeyer P, Vry M-S, Umarova R, Musso M, Glauche V, Abel S, Huber W, Rijntjes M, Hennig J, Weiller C. Ventral and dorsal pathways for language. Proc Natl Acad Sci U S A 2008; 105(45): 18035-18040. https://doi.org/10.1073/pnas.0805234105
   
   
3. Saur D, Ronneberger O, Kümmerer D, Mader I, Weiller C, Klöppel, S. Early fMRI activations predict language outcome after stroke. Brain 2010; 133; 1252-1264. https://doi.org/10.1093/brain/awq021
   
   
4. Kümmerer D, Hartwigsen G, Kellmeyer P, Glauche V, Mader I, Klöppel S, Suchan J, Karnath HO, Weiller C, Saur D. Damage to ventral and dorsal language pathways in acute aphasia. Brain 2013; 2: 619-629. https://doi.org/10.1093/brain/aws354
   
   
5. Hartwigsen G, Weigel A, Schuschan P, Siebner HR, Weise D, Classen J, Saur D. Dissociating Parieto-Frontal Networks for Phonological and Semantic Word Decisions: A Condition-and-Perturb TMS Study. Cereb Cortex 2016; 26: 2590-25601. https://doi.org/10.1093/cercor/bhv092
   
   
6. Hartwigsen G, Bzdok D, Klein M, Wawrzyniak M, Stockert A, Wrede K, Classen C, Saur D. Rapid short-term reorganisation in the language network. eLlife 2017; 6. https://doi.org/10.7554/eLife.25964.001
   
   
7. Hartwigsen G., Saur D. Neuroimaging of stroke recovery from aphasia – Insights into plasticity of the human language network. Neuroimage 2019; 190: 14-31. https://doi.org/10.1016/j.neuroimage.2017.11.056
   
   
8. Klingbeil J, Wawrzyniak M, Stockert A, Karnath HO, Saur D. Hippocampal diaschisis contributes to anosognosia for hemiplegia: evidence from lesion network-symptom mapping. Neuroimage 2020; 208: 116485. https://doi.org/10.1016/j.neuroimage.2019.116485
   
   
9. Stockert A, Wawrzyniak M, Klingbeil J, Wrede K, Kümmerer D, Hartwigsen G, Kaller CP, Weiller C, Saur D. Dynamics of language reorganization after left temporo-parietal and frontal stroke. Brain 2020; 143(3) 844-861. https://academic.oup.com/brain/article/143/3/844/5739979?guestAccessKey=a04f8eb1-d146-4812-a10f-13a381897264​
   
   
10. Hartwigsen G, Stockert A, Charpentier L, Wawrzyniak M, Klingbeil J, Wrede K, Obrig H, Saur D. Short-term modulation of the lesioned language network. eLife 2020; 9. https://doi.org/10.7554/eLife.54277.sa2​​

James S. McDonnell Foundation (JSMF): "Function, dysfunction and recovery of speech networks". 1/2012-12/2019 (Dorothee Saur)

Deutsche Forschungsgemeinschaft (German Research Foundation, DFG, SA 1723/5-1): "Cognitive and neurobiological characterization of deficit awareness in post-stroke aphasia" 1/2019-12/2021 (Dorothee Saur, Julian Klingbeil)​​

• Cathleen Höfer, cand. med.
  E-Mail: cathleen_hoefer@gmx.de
  
  Topic of doctoral thesis: Brain volumetric measurements and recording of verbal and spatial memory performance in patients with transient global amnesia​

• Sophia Hormig, cand. med.
  E-Mail: sophia.hormig@web.de
  
  Topic of doctoral thesis: Thalamic network pathology
  
   
•  Susann Machleb, cand. med.
  E-Mail: susann.machleb@medizin.uni-leipzig.de
  
  Topic of doctoral thesis: Deficit awareness in patients with aphasia: Monitoring of progress and neuronal correlates
  
   
• Max-Lennart Brandt, cand. med.
  E-Mail: max-lennart.brandt@medizin.uni-leipzig.de
  
  Topic of doctoral thesis: Neurobiological correlates of post-stroke depression: a lesion network study​
  
  
• Sandra Martin, cand. rer. nat.
  E-Mail: martin@cbs.mpg.de
  
  Topic of doctoral thesis: The domain-general network in language processing: Its role in the healthy brain and in language recovery in chronic post-stroke aphasia. 
  
  A cooperative project with the Max Planck Institute for Human Cognitive and Brain Sciences (Dr. phil. habil. Gesa Hartwigsen)
  
   
• Caroline Stephan, cand. med.
  E-Mail: caro_sn2000@yahoo.de
  
  Topic of doctoral thesis: Lesion network mapping of structural epilepsy after stroke
  
   
• Florian Welle, cand. med.
  E-Mail: Florian.Welle@medizin.uni-leipzig.de
  
  Topic of doctoral thesis: Multiparametric prediction of tissue outcome in patients with proximal intracranial vessel occlusion and mechanical recanalization​​
  
  
  
• Martin Mühlig, cand. med.
  E-Mail: martin.muehlig@t-online.de
  
  Topic of doctoral thesis: The role of overconfidence in anosognosia in neurological disorders​

• Max Wawrzyniak, MD
  
  Topic of doctoral thesis: Functional relevance and modulation of resting state connectivity in the semantic language network
  
  Defence: 26.04.2018​
  
  

• Anni Weigel, MD
  
  Topic of doctoral thesis: Contribution of frontal and parietal brain regions in semantic and phonological decisions: a TMS study
  
  Defence: 2.11.2017
  
   
• Christin Wendt, MD
  
  Topic of doctoral thesis: Temporo-frontal interactions in semantic integration: an fMRI-TMS study
  
  Defence: 2.11.2017
  
   
• Thomas Golombek, MD
  
  Topic of doctoral thesis: The role of the left angular gyrus in auditory language comprehension (in cooperation with the MPI for Human Cognitive and Brain Sciences)
  
  Defence: 5.02.2015
  
   
• Maren Klein, MD
  
  Topic of doctoral thesis: Modulation of phonological and semantic processes in the language network: a combined TMS-fMRI study
  
  Defence: 26.03.2015​​

We mainly assign experimental doctoral theses, whereby a semester on leave is usually necessary during the course of the thesis. Above-average commitment and a special interest in neuroscientific work are prerequisites for acceptance as a doctoral student. Participation in the weekly doctoral seminar (see lab meeting) is expected. Here, new projects, (interim) results and publications related to the various doctoral topics are presented.

If you are interested in a medical doctoral thesis on the topics of the research group, please send an E-mail with a meaningful curriculum vitae to dorothee.saur@medizin.uni-leipzig.de​​